PIPA535340

PIGR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA535340-Each-of-1 In Stock ₹ 47,528.58

PIPA535340 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

PIGR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pigr

Gene Alias

hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; phosphatidylinositol glycan, class R; Pigr; Poly Ig receptor; poly-Ig receptor; polymeric immunoglobulin receptor; Secretory component; tb6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5284

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P01833

Gene Symbols

Pigr

Immunogen

KLH conjugated synthetic peptide between 646-672 amino acids from the C-terminal region of human PIGR

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Polymeric IgA and IgM is produced and secreted by B cells in the lamina propria, which is beneath the mucosal lining of polarized epithelial cells
  • Polymeric immunoglobulin receptors, also designated pIgRs, are expressed on the basolateral surface of glandular epithelia and mediate transcellular transport of secretory immunoglobulin polymers across the epithelium
  • pIgR associates with secreted dimeric IgA and IgM molecules
  • During transcellular transport of these Ig polymers, pIgR undergoes proteolytic cleavage to generate a fragment called secretory component (SC), polymeric immunoglobulin receptor or poly-IG receptor
  • When immunoglobulin polymers associate with SC, they become resistant to enzymatic degradation during the transcytosis process
  • SC and the pIgR are crucial for proper mucosal immunity where they represent a molecular chaperone for polymeric Igs to remain intact and enter into body fluids
  • The human SC (pIgR) gene maps to chromosome 1q31-q41 and encodes a 764 amino acid protein
  • The receptor contains five units with homology to the variable (V) units of immunoglobulins and a transmembrane region that shares homology to certain immunoglobulin variable regions.

Compare Similar Items

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Img

Thermo Scientific

PIPA535340

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Antigen:
PIGR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pigr

Gene Alias:
hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; phosphatidylinositol glycan, class R; Pigr; Poly Ig receptor; poly-Ig receptor; polymeric immunoglobulin receptor; Secretory component; tb6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5284

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P01833

Gene Symbols:
Pigr

Immunogen:
KLH conjugated synthetic peptide between 646-672 amino acids from the C-terminal region of human PIGR

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA535341

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Antigen:
SCAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCAP

Gene Alias:
9530044G19; EMBL:AAI31853.1}; KIAA0199; mKIAA0199; PSEC0227; SCAP; scap {ECO:0000312; Sreb cleavage-activating protein; SREBF chaperone; SREBP cleavage activating protein; SREBP cleavage-activating protein; sterol regulatory element binding protein cleavage-activating protein; sterol regulatory element-binding protein cleavage-activating protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22937

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q12770

Gene Symbols:
SCAP

Immunogen:
KLH conjugated synthetic peptide between 604-632 amino acids from the central region of human SCAP

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA535343

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Antigen:
IGFBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3485

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P18065

Gene Symbols:
IGFBP2

Immunogen:
KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human IGFBP2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA535344

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Antigen:
WNT5B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WNT5B

Gene Alias:
AW545702; protein Wnt-5b; wingless-related MMTV integration site 5B; wingless-type MMTV integration site family member 5B; wingless-type MMTV integration site family, member 5B; Wnt family member 5B; WNT5B; Wnt-5b; WNT-5B protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22419, 81029

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P22726, Q9H1J7

Gene Symbols:
WNT5B

Immunogen:
KLH conjugated synthetic peptide between 153-182 amino acids from the central region of human WNT5B

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG