PIPA535413

Phospho-PTPN3 (Ser459) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA535413-Each-of-1 In Stock ₹ 44,705.10

PIPA535413 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-PTPN3 (Ser459)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN3

Gene Alias

9530011I20Rik; cytoskeletal-associated protein tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 3; protein-tyrosine phosphatase H1; PTPCL; PTPH1; PTP-H1; Ptpn3; Tyrosine-protein phosphatase non-receptor type 3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

545622, 5774

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.25 mg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

A2ALK8, P26045

Gene Symbols

PTPN3

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser459 of human PTPH1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, non-human primate and sheep based on 100% sequence homology
  • This antibody contains enough material to conduct 10 mini-Western blots
  • Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases
  • Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli
  • Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation - it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events
  • Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders
  • Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors
  • Most protein phosphatases are not stringently specific for their substrates
  • Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases
  • This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA535413

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Antigen:
Phospho-PTPN3 (Ser459)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN3

Gene Alias:
9530011I20Rik; cytoskeletal-associated protein tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 3; protein-tyrosine phosphatase H1; PTPCL; PTPH1; PTP-H1; Ptpn3; Tyrosine-protein phosphatase non-receptor type 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
545622, 5774

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
A2ALK8, P26045

Gene Symbols:
PTPN3

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser459 of human PTPH1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA535414

--


Antigen:
Phospho-Dopamine Transporter (Thr53)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slc6a3

Gene Alias:
DA transporter; Dat; Dat1; dopamine transporter; dopamine transporter 1; PKDYS; SLC6A3; Sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; solute carrier family 6 member 3; solute carrier family 6, member 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13162, 24898

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P23977, Q61327

Gene Symbols:
Slc6a3

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr53 of rat SLC6A3 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA535415

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Antigen:
Hepatitis C Virus E1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
HCV E1; HCV genotype 2A; HepC

Host Species:
Goat

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
4-5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Hepatitis C virus recombinant protein

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

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PIPA535848

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Antigen:
ADPRHL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADPRHL1

Gene Alias:
[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADPRHL1; ADP-ribosylarginine hydrolase like 1; ADP-ribosyl-hydrolase; ADP-ribosylhydrolase 2; ADP-ribosylhydrolase like 1; Arh2; D330008N11Rik

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
113622, 234072

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8BGK2, Q8NDY3

Gene Symbols:
ADPRHL1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 35 and 294 of ADPRHL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG