PIPA538284

Phospho-IRAK1 (Thr387) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538284-Each-of-1 In Stock ₹ 42,352.20

PIPA538284 - Each of 1

₹ 42,352.20

In Stock

Quantity

1

Base Price: ₹ 42,352.20

GST (18%): ₹ 7,623.396

Total Price: ₹ 49,975.596

Antigen

Phospho-IRAK1 (Thr387)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRAK1

Gene Alias

IL-1 Receceptor Associated Kinase, Interleukin-1 receptor-associated kinase 1, mPLK, IRAK, pelle, Pelle homolog, Pelle

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16179, 363520, 3654

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P51617, Q62406

Gene Symbols

IRAK1

Immunogen

A synthetic phosphopeptide derived from human IRAK1 around the phosphorylation site of Thr387 (R-G-TP-L-A)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Interleukin-1 receptor-associated kinase 1 (IRAK1) is a serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens
  • IRAK is associated with Toll-like receptor (TLR) and IL-1R signaling pathways
  • It is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation
  • IRAK′s association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation
  • Alternatively, IRAK1 can phosphorylate TIRAP to promote its ubiquitination and subsequent degradation
  • IRAK1 also phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus
  • This results in the transcriptional activiation of type I IFN genes, which drive the cell in an antiviral state.

Compare Similar Items

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Img

Thermo Scientific

PIPA538284

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Antigen:
Phospho-IRAK1 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRAK1

Gene Alias:
IL-1 Receceptor Associated Kinase, Interleukin-1 receptor-associated kinase 1, mPLK, IRAK, pelle, Pelle homolog, Pelle

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 363520, 3654

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51617, Q62406

Gene Symbols:
IRAK1

Immunogen:
A synthetic phosphopeptide derived from human IRAK1 around the phosphorylation site of Thr387 (R-G-TP-L-A)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538286

--


Antigen:
Phospho-IRS1 (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
Insulin receptor substrate 1, IRS-1, IRS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
A synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Ser323 (P-G-SP-F-R)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538289

--


Antigen:
JNK1/JNK2/JNK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK9

Gene Alias:
JNK 46, JNK 55, JNK, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2ALPHA, JNK2B, JNK2BETA, JNK3, JNK3A, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 8, MAPK 9, MAPK10, MAPK8, MAPK9, MGC50974, Mitogen activated protein kinase 10, Mitogen activated protein kinase 8, Mitogen activated protein kinase 9, JNK3; JNK3A; PRKM10; p54bSAPK; MAPK10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P45983, P45984, P53779, Q61831, Q91Y86, Q9WTU6, P49185, P49186, P49187

Gene Symbols:
MAPK10, MAPK8, MAPK9

Immunogen:
A synthetic non-phosphopeptide derived from human JNK1/2/3 around the phosphorylation site of Thr183/Tyr185 (M-M-TP-P-YP-V-V)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538294

--


Antigen:
MiTF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MITF

Gene Alias:
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17342, 4286

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75030, Q08874

Gene Symbols:
MITF

Immunogen:
A synthetic non-phosphopeptide derived from human MITF around the phosphorylation site of Ser180/73 (P-N-SP-P-M)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG