PIPA538371

MSK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538371-Each-of-1 In Stock ₹ 42,694.44

PIPA538371 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

MSK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RPS6KA5

Gene Alias

Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5, MSK1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

73086, 9252

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75582, Q8C050

Gene Symbols

RPS6KA5

Immunogen

A synthetic non-phosphopeptide derived from human MSK1 around the phosphorylation site of Thr581 (L-K-TP-P-C)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA538368

--

Img

Thermo Scientific

PIPA538330

--

Img

Thermo Scientific

PIPA538920

--

Img

Thermo Scientific

PIPA538593

--

Img

Thermo Scientific

PIPA538976

--

Img

Thermo Scientific

PIPA538335

--

Img

Thermo Scientific

PIPA538294

--

Img

Thermo Scientific

PIPA538466

--

Description

  • MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily
  • MSK-1can be activated by ERK1/2 and SAPK2 /p38 MAP kinase
  • It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress
  • Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term)
  • Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites
  • Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538371

--


Antigen:
MSK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS6KA5

Gene Alias:
Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5, MSK1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
73086, 9252

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75582, Q8C050

Gene Symbols:
RPS6KA5

Immunogen:
A synthetic non-phosphopeptide derived from human MSK1 around the phosphorylation site of Thr581 (L-K-TP-P-C)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538378

--


Antigen:
Phospho-p130Cas (Tyr249)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCAR1

Gene Alias:
Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, BCAR1, CAS, CASS1, CRKAS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12927, 25414, 9564

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P56945, Q61140, Q63767

Gene Symbols:
BCAR1

Immunogen:
A synthetic phosphopeptide derived from human p130 Cas around the phosphorylation site of Tyr249 (D-I-YP-D-V)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538381

--


Antigen:
Phospho-PAK2 (Ser20)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK2

Gene Alias:
Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK1, PAK alpha, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK-2p27, PAK-2p34, C-t-PAK2, PAK2, PAK gamma, Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, PAK beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224105, 29432, 5062

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13177, Q8CIN4, Q64303

Gene Symbols:
PAK2

Immunogen:
A synthetic phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20 (M-S-SP-T-I)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538383

--


Antigen:
Phospho-PIN1 (Ser16)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIN1

Gene Alias:
EC 5.2.1.8, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Rotamase Pin1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23988, 5300

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13526, Q9QUR7

Gene Symbols:
PIN1

Immunogen:
A synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16 (R-M-SP-R-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG