PIPA538461

Phospho-CXCR4 (Ser339) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538461-Each-of-1 In Stock ₹ 43,892.28

PIPA538461 - Each of 1

₹ 43,892.28

In Stock

Quantity

1

Base Price: ₹ 43,892.28

GST (18%): ₹ 7,900.61

Total Price: ₹ 51,792.89

Antigen

Phospho-CXCR4 (Ser339)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CXCR4

Gene Alias

D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, C-X-C chemokine receptor type 4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12767, 7852

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P61073, P70658

Gene Symbols

CXCR4

Immunogen

A synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser339 (H-S-SP-V-S)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells
  • Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors
  • Among them, CXCR4 (fusin, LESTR or HUMSTR) is a principal coreceptor for T-cell tropic strains of HIV-1 fusion and entry of human white blood cells
  • CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD-4 independent infection by HIV-2
  • The a-chemokine SDF-1 is the ligand for CXCR4 and prevents infection by T-tropic HIV-1
  • CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells
  • CXCR4 messenger RNA levels correlated with HIV-1 permissiveness in diverse human cell types
  • Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
  • The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538461

--


Antigen:
Phospho-CXCR4 (Ser339)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXCR4

Gene Alias:
D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, C-X-C chemokine receptor type 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12767, 7852

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P61073, P70658

Gene Symbols:
CXCR4

Immunogen:
A synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser339 (H-S-SP-V-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538462

--


Antigen:
Phospho-Cyclin E2 (Thr392)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCNE2

Gene Alias:
CYCE2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12448, 9134

Content And Storage:
-20°C

Form:
Liquid

Applications:
Peptide ELISA, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O96020, Q9Z238

Gene Symbols:
CCNE2

Immunogen:
A synthetic phosphopeptide derived from human Cyclin E2 around the phosphorylation site of Thr392 (I-M-TP-P-P)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538464

--


Antigen:
Phospho-Cytokeratin 8 (Ser432)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT8

Gene Alias:
CK 8, CK8, CYK8, Cytokeratin endo A, K2C8, K8, KRT2-8, KRT8, Keratin, type II cytoskeletal 8, cytokeratin 8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16691, 25626, 3856

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05787, P11679, Q10758

Gene Symbols:
KRT8

Immunogen:
A synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Ser431 (L-T-SP-P-G)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538466

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Antigen:
Phospho-DAPK2 (Ser318)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAPK2

Gene Alias:
DRP-1, DRP1, DAP kinase 2, DAP-kinase-related protein 1 beta isoform

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13143, 23604

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UIK4, Q8VDF3

Gene Symbols:
DAPK2

Immunogen:
A synthetic phosphopeptide derived from human DAPK2 around the phosphorylation site of Ser318 (K-L-SP-F-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG