PIPA538501

Phospho-ErbB4 (Tyr1284) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538501-Each-of-1 In Stock ₹ 42,523.32

PIPA538501 - Each of 1

₹ 42,523.32

In Stock

Quantity

1

Base Price: ₹ 42,523.32

GST (18%): ₹ 7,654.198

Total Price: ₹ 50,177.518

Antigen

Phospho-ErbB4 (Tyr1284)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

HER4, p180erbB4, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, tyrosine kinase-type cell surface receptor HER4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13869, 2066, 59323

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15303, Q61527, Q62956

Gene Symbols

ERBB4

Immunogen

A synthetic phosphopeptide derived from human HER4/ErbB4 around the phosphorylation site of Tyr1284 (P-E-YP-L-S)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family
  • With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes
  • The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predomitly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some maligcies.

Compare Similar Items

Show Difference

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PIPA538501

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Antigen:
Phospho-ErbB4 (Tyr1284)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
HER4, p180erbB4, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, tyrosine kinase-type cell surface receptor HER4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066, 59323

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15303, Q61527, Q62956

Gene Symbols:
ERBB4

Immunogen:
A synthetic phosphopeptide derived from human HER4/ErbB4 around the phosphorylation site of Tyr1284 (P-E-YP-L-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538506

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Antigen:
NMDAR2A/NMDAR2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN2B

Gene Alias:
NMDAR2A, NR2A, N-Methyl-D-Aspartate Receptor Type 2A, Grin2a, GluN2A, Glutamate receptor ionotropic NMDA 2A, Glutamate NMDA receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, Glutamate [NMDA] receptor subunit epsilon 2 precursor, GRIN2B, hNR3, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDE2, NME2, NR2B, NR3, NMDAR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14811, 14812, 24409, 24410, 2903, 2904

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q12879, Q13224, P35436, Q01097, Q00959, Q00960

Gene Symbols:
GRIN2A, GRIN2B

Immunogen:
A synthetic peptide derived from the internal region of human NMDAR2A/B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538514

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Antigen:
Nkx6.3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKX6-3

Gene Alias:
NKX6-3, Homeobox protein Nkx-6.3, NKX6.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
157848, 74561

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A6NJ46, Q3UHX8

Gene Symbols:
NKX6-3

Immunogen:
A synthetic peptide derived from the internal region of human NKX63

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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PIPA538516

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Antigen:
TRIM38

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM38

Gene Alias:
RNF15, RORET

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10475, 214158

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O00635

Gene Symbols:
TRIM38

Immunogen:
A synthetic peptide derived from the internal region of human TRIM38

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG