PIPA538779
NPM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA538779-Each-of-1 | In Stock | ₹ 42,694.44 |
PIPA538779 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,694.44
GST (18%): ₹ 7,684.999
Total Price: ₹ 50,379.439
Antigen
NPM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
Nucleophosmin, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18148, 25498, 4869
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P06748, Q61937, P13084
Gene Symbols
NPM1
Immunogen
A synthetic peptide derived from the N-terminal region of human NPM
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
Compare Similar Items
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Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: Nucleophosmin, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P06748, Q61937, P13084
Gene Symbols: NPM1
Immunogen: A synthetic peptide derived from the N-terminal region of human NPM
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
Nucleophosmin, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P06748, Q61937, P13084
Gene Symbols:
NPM1
Immunogen:
A synthetic peptide derived from the N-terminal region of human NPM
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PKIB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKIB
Gene Alias: PRKACN2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18768, 24678, 5570
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9C010, Q04758, P27775
Gene Symbols: PKIB
Immunogen: A synthetic peptide derived from the internal region of human IPKB
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PKIB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKIB
Gene Alias:
PRKACN2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18768, 24678, 5570
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9C010, Q04758, P27775
Gene Symbols:
PKIB
Immunogen:
A synthetic peptide derived from the internal region of human IPKB
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF436
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF436
Gene Alias: KIAA1710
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80818
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9C0F3
Gene Symbols: ZNF436
Immunogen: A synthetic peptide derived from the internal region of human ZNF436
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF436
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF436
Gene Alias:
KIAA1710
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80818
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9C0F3
Gene Symbols:
ZNF436
Immunogen:
A synthetic peptide derived from the internal region of human ZNF436
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PBOV1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PBOV1
Gene Alias: UROC28
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 59351
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9GZY1
Gene Symbols: PBOV1
Immunogen: A synthetic peptide derived from the internal region of human PBOV1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PBOV1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PBOV1
Gene Alias:
UROC28
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
59351
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9GZY1
Gene Symbols:
PBOV1
Immunogen:
A synthetic peptide derived from the internal region of human PBOV1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG