PIPA551516

C14orf126 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA551516-Each-of-1 In Stock ₹ 47,015.22

PIPA551516 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

C14orf126

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DTD2

Gene Alias

4930578F06Rik; 6530401N04Rik; Animalia-specific tRNA deacylase; ATD; B830049N13Rik; C14orf126; D-aminoacyl-tRNA deacylase 2; DTD2; D-tyrosyl-tRNA deacylase 2; D-tyrosyl-tRNA deacylase 2 (putative); D-tyrosyl-tRNA(Tyr) deacylase 2; L-alanyl-tRNA deacylase; probable D-tyrosyl-tRNA(Tyr) deacylase 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

112487

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96FN9

Gene Symbols

DTD2

Immunogen

Recombinant protein corresponding to Human C14orf126

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: WVEVQRGLVI YVCFFKGADK ELLPKMVNTL LNVKLSETEN GKHVSILDLP GNILIIPQAT LGGRLKGRNM QYHSNSGKEE GFELYSQFVT LCEKEVAANS KCAEARVVVE HGTYGNRQVL KLDTNGPFTH LIFE Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%
  • Deacylates mischarged D-aminoacyl-tRNAs
  • Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS
  • Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids
  • Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr), has no activity on correctly charged L-tyrosyl-tRNA(Tyr)
  • By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
  • In contrast to DTD1, deacylates L-Ala mischarged on tRNA(Thr)(G4.U69) by alanine-tRNA ligase AARS (PubMed:29410408)
  • Can deacylate L-Ala due to a relaxed specificity for substrate chirality caused by the trans conformation of the Gly-Pro motif in the active site (PubMed:29410408)
  • Also hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly) in vitro, although in vivo EEF1A1/EF-Tu may protect cognate achiral glycyl-tRNA(Gly) from DTD2-mediated deacetylation
  • [UniProt]

Compare Similar Items

Show Difference

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PIPA551516

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Antigen:
C14orf126

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DTD2

Gene Alias:
4930578F06Rik; 6530401N04Rik; Animalia-specific tRNA deacylase; ATD; B830049N13Rik; C14orf126; D-aminoacyl-tRNA deacylase 2; DTD2; D-tyrosyl-tRNA deacylase 2; D-tyrosyl-tRNA deacylase 2 (putative); D-tyrosyl-tRNA(Tyr) deacylase 2; L-alanyl-tRNA deacylase; probable D-tyrosyl-tRNA(Tyr) deacylase 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112487

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96FN9

Gene Symbols:
DTD2

Immunogen:
Recombinant protein corresponding to Human C14orf126

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA551519

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Antigen:
RNase1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNASE1

Gene Alias:
AI574248; HP-RNase; RAC1; Rib 1; RIB1; Rib-1; Ribonuclease 1; ribonuclease 1, pancreatic; ribonuclease A; ribonuclease A (pancreatic); ribonuclease A C1; ribonuclease A family member 1, pancreatic; ribonuclease BS-1; Ribonuclease pancreatic; ribonuclease, RNase A family, 1 (pancreatic); RNase 1; RNase A; RNase upI-1; RNASE1; RNAseA; RNS1; Seminal ribonuclease; seminal RNase; seminal RNase (aa 47-124); SRN; S-RNase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6035

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P07998

Gene Symbols:
RNASE1

Immunogen:
Recombinant protein corresponding to Human RNase1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA551520

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Antigen:
VCPKMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VCPKMT

Gene Alias:
C14orf138; methyltransferase like 21D; methyltransferase-like protein 21D; METTL21D; Protein-lysine methyltransferase METTL21D; valosin containing protein lysine (K) methyltransferase; valosin containing protein lysine methyltransferase; valosin-containing protein lysine methyltransferase; VCP lysine methyltransferase; VCPKMT; VCP-KMT

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H867

Gene Symbols:
VCPKMT

Immunogen:
Recombinant protein corresponding to Human VCPKMT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA551522

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Antigen:
JOSD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JOSD1

Gene Alias:
1300006C06Rik; dJ508I15.2; Josd1; Josephin domain containing 1; josephin domain-containing 1; josephin domain-containing protein 1; Josephin-1; Josephin-1; josephin-1; JSPH1; KIAA0063; KIAA0063 gene product; mKIAA0063; RGD1305388; zgc:153682

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9929

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
Lot-Specific

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q15040

Gene Symbols:
JOSD1

Immunogen:
Recombinant protein corresponding to Human JOSD1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG