PIPA551562

DNA ligase IV Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA551562-Each-of-1 In Stock ₹ 47,015.22

PIPA551562 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

DNA ligase IV

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LIG4

Gene Alias

5830471N16Rik; DNA joinase; DNA ligase (ATP) 4; DNA ligase 4; DNA ligase IV; DNA repair enzyme; Lig4; LIG4S; ligase IV, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 4; polynucleotide ligase; sealase; tiny

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3981

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P49917

Gene Symbols

LIG4

Immunogen

Recombinant protein corresponding to Human DNA ligase IV

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: TYCVIAGSEN IRVKNIILSN KHDVVKPAWL LECFKTKSFV PWQPRFMIHM CPSTKEHFAR EYDCYGDSYF IDTDLNQLKE VFSGIKNSNE QTPEEMASLI ADLEYRYSWD CSPLSMFRRH TVYLDSYA Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%
  • The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction
  • This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ)
  • This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK)
  • Both XRCC4 and DNA-PK are known to be required for NHEJ
  • The crystal structure of the complex formed by this protein and XRCC4 has been resolved
  • Defects in this gene are the cause of LIG4 syndrome
  • Alternatively spliced transcript variants encoding the same protein have been observed.

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Thermo Scientific

PIPA551562

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Antigen:
DNA ligase IV

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LIG4

Gene Alias:
5830471N16Rik; DNA joinase; DNA ligase (ATP) 4; DNA ligase 4; DNA ligase IV; DNA repair enzyme; Lig4; LIG4S; ligase IV, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 4; polynucleotide ligase; sealase; tiny

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3981

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P49917

Gene Symbols:
LIG4

Immunogen:
Recombinant protein corresponding to Human DNA ligase IV

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA551563

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Antigen:
Ymer

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccdc50

Gene Alias:
C3orf6; C3orf6h; Ccdc50; coiled-coil domain containing 50; coiled-coil domain-containing protein 50; DFNA44; Protein Ymer; putative C3orf6 protein homolog; YMER; Ymer protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
152137, 288022, 67501

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q810U0, Q810U5, Q8IVM0

Gene Symbols:
Ccdc50

Immunogen:
Recombinant protein corresponding to Human Ymer

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA551564

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Antigen:
MYH6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYH6

Gene Alias:
A830009F23Rik; AA517445; alpha cardiac MHC; alpha myosin; alpha-MHC; ASD3; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; CMD1EE; CMH14; MYH6; MYHC; Myhca; Myhc-a; MyHC-alpha; myosin 6; Myosin heavy chain 6; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin-6; SSS3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4624

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.10 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P13533

Gene Symbols:
MYH6

Immunogen:
Recombinant protein corresponding to Human MYBPC2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA551565

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Antigen:
STX5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STX5

Gene Alias:
0610031F24Rik; D19Ertd627e; SED5; Stx5; Stx5a; syntaxin 5; syntaxin 5A; syntaxin-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6811

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q13190

Gene Symbols:
STX5

Immunogen:
Recombinant protein corresponding to Human STX5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG