PIPA551586

PTS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA551586-Each-of-1 In Stock ₹ 47,015.22

PIPA551586 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

PTS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pts

Gene Alias

6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5805

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q03393

Gene Symbols

Pts

Immunogen

Recombinant protein corresponding to Human PTS

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA554414

--

Img

Thermo Scientific

PIPA554364

--

Img

Thermo Scientific

PIPA554454

--

Img

Thermo Scientific

PIPA584820

--

Img

Thermo Scientific

PIPA551631

--

Img

Thermo Scientific

PIPA561522

--

Img

Thermo Scientific

PIPA551886

--

Img

Thermo Scientific

PIPA5110834

--

Description

  • Immunogen sequence: RCQAQVSRRI SFSASHRLYS KFLSDEENLK LFGKCNNPNG HGHNYKVVVT VHGEIDPATG MVMNLADLKK YMEEAIMQPL DHKNLDMDVP YFADVVSTTE NVAVYIWDNL QKVLPVGVLY KVKVYETDNN IV Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%
  • The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis
  • BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase
  • BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis
  • The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89
  • The active site of PTPS undergoes a Zn and Mg-dependent reaction that includes a triphosphate elimination, a stereospecific reduction and the oxidation of both side hydroxyl groups
  • The catalytic triad of PTPS is involved in the deprotonation of the side-chain carbons of substrates
  • In addition, Ser 19 of human PTPS may be a substrate for cGMP-dependent protein kinase type II phosphorylation in vivo, which is essential for normal activity of PTPS.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA551586

--


Antigen:
PTS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pts

Gene Alias:
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q03393

Gene Symbols:
Pts

Immunogen:
Recombinant protein corresponding to Human PTS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551588

--


Antigen:
ZNF229

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF229

Gene Alias:
Zinc finger protein 229; ZNF229

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7772

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UJW7

Gene Symbols:
ZNF229

Immunogen:
Recombinant protein corresponding to Human ZNF229

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551589

--


Antigen:
alpha-1 Microglobulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBP

Gene Alias:
A1M; AI194774; alpha 1 microglobulin/bikunin; alpha-1 microglobulin; Alpha-1 microglobulin/bikunin; Alpha-1 microglycoprotein; Alpha-1-microglobulin; alpha-1-microglobulin/bikunin; alpha1-microglobulin/bikunin; alpha-1-microglobulin/bikunin precursor; alpha-1-microglobulin-bikunin; alpha1-microglobulin-bikunin precursor; Ambp; AMBP protein; ASPI; BI-14; Bikunin; complex-forming glycoprotein heterogeneous in charge; Cumulus extracellular matrix-stabilizing factor; EDC1; ESF; growth-inhibiting protein 19; HCP; HI30; HI-30; IATIL; inter-alpha-trypsin inhibitor (protein HC), light; inter-alpha-trypsin inhibitor light chain; Intin4; ITI; ITIL; ITILC; ITI-LC; polyprotein; protein AMBP; Protein HC; Protein Protein HC; trypstatin; μginastatin; unnamed protein product; Urinary Trypsin Inhibitor; uristatin; uronic-acid-rich protein; UTI

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P02760

Gene Symbols:
AMBP

Immunogen:
Recombinant protein corresponding to Human alpha-1 Microglobulin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551590

--


Antigen:
SMC1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smc1b

Gene Alias:
bK268H5; bK268H5.5; mitosis-specific chromosome segregation protein like protein beta; RP1-102D24.3; SMC; SMC protein 1B; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 structural maintenance of chromosomes 1-like 2; SMC1B; SMC-1B; SMC1BETA; SMC-1-beta; SMC1L2; structural maintenace of chromosomes 1B; structural maintenance of chromosomes 1B; structural maintenance of chromosomes protein 1B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27127

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8NDV3

Gene Symbols:
Smc1b

Immunogen:
Recombinant protein corresponding to Human SMC1B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG