PIPA551688

GART Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA551688-Each-of-1 In Stock ₹ 47,015.22

PIPA551688 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

GART

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GART

Gene Alias

5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; Gaps; GAR transformylase; GARS; Gart; GARTF; glycinamide ribonucleotide formyltransferase; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosylamine--glycine ligase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; Trifunctional purine biosynthetic protein adenosine-3; Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14450, 2618, 288259

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P22102, Q64737

Gene Symbols

GART

Immunogen

Recombinant protein corresponding to Human GART

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: IEFVVVGPEA PLAAGIVGNL RSAGVQCFGP TAEAAQLESS KRFAKEFMDR HGIPTAQWKA FTKPEEACSF ILSADFPALV VKASGLAAGK GVIVAKSKEE ACKAVQEIMQ EKAFGAAGET IVIEELLDGE EVSCLCFTDG KTV Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%
  • MERTK is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
  • Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
  • Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
  • MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
  • Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
  • Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Compare Similar Items

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Img

Thermo Scientific

PIPA551688

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Antigen:
GART

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GART

Gene Alias:
5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; Gaps; GAR transformylase; GARS; Gart; GARTF; glycinamide ribonucleotide formyltransferase; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosylamine--glycine ligase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; Trifunctional purine biosynthetic protein adenosine-3; Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14450, 2618, 288259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P22102, Q64737

Gene Symbols:
GART

Immunogen:
Recombinant protein corresponding to Human GART

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551689

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Antigen:
FAM62B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ESYT2

Gene Alias:
2410017M09Rik; 4921504I16Rik; chr2 synaptotagmin; CHR2SYT; D12Ertd551e; ESYT2; E-Syt2; extended synaptotagmin 2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; extended synaptotagmin-2; extended synaptotagmin-like protein 2; Fam62b; family with sequence similarity 62 (C2 domain containing), member B; family with sequence similarity 62, member B; KIAA1228; RGD1565705

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57488

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A0FGR8

Gene Symbols:
ESYT2

Immunogen:
Recombinant protein corresponding to Human FAM62B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551690

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Antigen:
IFI16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFI16

Gene Alias:
gamma-interferon-inducible protein 16; IFI 16C; IFI16; Ifi-16; IFNGIP1; interferon gamma inducible protein 16; interferon, gamma-inducible protein 16; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; PYHIN2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3428

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q16666

Gene Symbols:
IFI16

Immunogen:
Recombinant protein corresponding to Human IFI16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA551692

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Antigen:
LONP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LONP1

Gene Alias:
1200017E13Rik; CODASS; h LonHS; HAMAP-Rule:MF_03120}; hLON; hLON ATP-dependent protease; Lon; lon peptidase 1, mitochondrial; lon protease homolog, mitochondrial; lon protease homolog, mitochondrial {ECO:0000255; Lon protease-like protein; lon protease-like protein {ECO:0000255; LONHs; LONP; LONP {ECO:0000255; LONP1; Mitochondrial ATP-dependent protease Lon; mitochondrial ATP-dependent protease Lon {ECO:0000255; mitochondrial lon protease-like protein; PIM1; protease, serine, 15; Prss15; Serine protease 15; serine protease 15 {ECO:0000255

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170916, 74142, 9361

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.30 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P36776, Q8CGK3, Q924S5

Gene Symbols:
LONP1

Immunogen:
Recombinant protein corresponding to Human LONP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG