PIPA551770
EXD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA551770-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA551770 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
EXD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EXD2
Gene Alias
3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55218
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9NVH0
Gene Symbols
EXD2
Immunogen
Recombinant protein corresponding to Human EXD2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: SKTSPVTQQP QQKVLGSREL PPPEDDQLHS SAPRSSWKER ILKAKVVTVS QEAEWDQIEP LLRSELEDFP VLGIDCEWER HGTYLQWLF Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 58%
- Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291)
- In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn(2+) (PubMed:29335528, PubMed:31127291)
- Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation (PubMed:29335528)
- Also involved in the response to DNA damage (PubMed:26807646, PubMed:31255466)
- Acts as 3'-5' exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073, PubMed:26807646)
- Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks (PubMed:26807646)
- Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression, thereby suppressing their degradation (PubMed:31255466)
- [UniProt]
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Antigen: EXD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXD2
Gene Alias: 3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55218
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NVH0
Gene Symbols: EXD2
Immunogen: Recombinant protein corresponding to Human EXD2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EXD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXD2
Gene Alias:
3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55218
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NVH0
Gene Symbols:
EXD2
Immunogen:
Recombinant protein corresponding to Human EXD2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AADAC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AADAC
Gene Alias: 5033417E09Rik; Aada; AADAC; AI265437; Arylacetamide deacetylase; arylacetamide deacetylase (esterase); CES5A1; DAC
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: Lot-Specific
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P22760
Gene Symbols: AADAC
Immunogen: Recombinant protein corresponding to Human AADAC
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
AADAC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AADAC
Gene Alias:
5033417E09Rik; Aada; AADAC; AI265437; Arylacetamide deacetylase; arylacetamide deacetylase (esterase); CES5A1; DAC
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
Lot-Specific
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P22760
Gene Symbols:
AADAC
Immunogen:
Recombinant protein corresponding to Human AADAC
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PHKA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PHKA2
Gene Alias: 6330505C01Rik; D330034O08; GSD9A; Phk; Phka2; PHKLA; phosphorylase b kinase regulatory subunit alpha liver isoform; phosphorylase b kinase regulatory subunit alpha, liver isoform; phosphorylase kinase; phosphorylase kinase alpha 2; phosphorylase kinase alpha L subunit; phosphorylase kinase alpha-subunit; phosphorylase kinase regulatory subunit alpha 2; phosphorylase kinase, alpha 2; phosphorylase kinase, alpha 2 (liver); PYK; PYKL; RP3-499B10.2; XLG; XLG2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5256
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P46019
Gene Symbols: PHKA2
Immunogen: Recombinant protein corresponding to Human PHKA2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHKA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PHKA2
Gene Alias:
6330505C01Rik; D330034O08; GSD9A; Phk; Phka2; PHKLA; phosphorylase b kinase regulatory subunit alpha liver isoform; phosphorylase b kinase regulatory subunit alpha, liver isoform; phosphorylase kinase; phosphorylase kinase alpha 2; phosphorylase kinase alpha L subunit; phosphorylase kinase alpha-subunit; phosphorylase kinase regulatory subunit alpha 2; phosphorylase kinase, alpha 2; phosphorylase kinase, alpha 2 (liver); PYK; PYKL; RP3-499B10.2; XLG; XLG2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5256
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P46019
Gene Symbols:
PHKA2
Immunogen:
Recombinant protein corresponding to Human PHKA2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EAPP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EAPP
Gene Alias: 1810011O16Rik; BM036; BM-036; c14orf11; E2F associated phosphoprotein; E2F-associated phosphoprotein; Eapp; hypothetical protein LOC327318; RGD1309624; Unknown (protein for MGC:139672); wu:fd21g02; zgc:65820
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55837
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q56P03
Gene Symbols: EAPP
Immunogen: Recombinant protein corresponding to Human EAPP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EAPP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EAPP
Gene Alias:
1810011O16Rik; BM036; BM-036; c14orf11; E2F associated phosphoprotein; E2F-associated phosphoprotein; Eapp; hypothetical protein LOC327318; RGD1309624; Unknown (protein for MGC:139672); wu:fd21g02; zgc:65820
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55837
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q56P03
Gene Symbols:
EAPP
Immunogen:
Recombinant protein corresponding to Human EAPP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG