PIPA552396
PTPRN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA552396-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA552396 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
PTPRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPRN
Gene Alias
105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5798
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q16849
Gene Symbols
PTPRN
Immunogen
Recombinant protein corresponding to Human PTPRN
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: HSYGDLPGPS PAQLFQDSGL LYLAQELPAP SRARVPRLPE QGSSSRAEDS PEGYEKEGLG DRGEKPASPA VQPDAALQRL AAVLAGYGVE LRQLTPEQLS TLLTLLQLLP KGA Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 81%
- IA-2 (insulinoma-associated protein 2, ICA512, PTPRN) is a member of the transmembrane protein tyrosine phosphatase (PTP) family located in secretory granules of neuroendocrine cells
- The IA-2 protein is 979 amino acids in length and consists of a luminal domain, transmembrane domain, and cytoplasmic domain
- Although a member of the PTP family, IA-2 lacks phosphatase activity with known substrates due to amino acid substitutions at critical sites in its PTP domain
- Two paralog RPTPs, IA-2 and IA-2beta were identified as major autoantigens in type-1 diabetes mellitus
- On granule exocytosis, the IA-2 cytoplasmic domain is cleaved and the resulting cytosolic fragment moves into the nucleus where it enhances the levels of phosphorylated STAT5 and STAT3, thereby inducing insulin gene transcription and granule biogenesis
- IA-2 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
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Antigen: PTPRN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRN
Gene Alias: 105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5798
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q16849
Gene Symbols: PTPRN
Immunogen: Recombinant protein corresponding to Human PTPRN
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTPRN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRN
Gene Alias:
105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5798
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q16849
Gene Symbols:
PTPRN
Immunogen:
Recombinant protein corresponding to Human PTPRN
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SERCA3 ATPase
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Atp2a3
Gene Alias: adenosine triphosphatase, calcium; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SERCA3b; SR Ca(2+)-ATPase 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 489
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q93084
Gene Symbols: Atp2a3
Immunogen: Recombinant protein corresponding to Human SERCA3 ATPase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SERCA3 ATPase
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Atp2a3
Gene Alias:
adenosine triphosphatase, calcium; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SERCA3b; SR Ca(2+)-ATPase 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
489
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q93084
Gene Symbols:
Atp2a3
Immunogen:
Recombinant protein corresponding to Human SERCA3 ATPase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SULT1C2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SULT1C2
Gene Alias: (PST)G; 1810008N17Rik; 1C member 4; HAST-I; humSULTC2; LOC100729651; MGC149521; MGC34422; mOLFST; N-hydroxyarylamine sulfotransferase; N-hydroxylarylamine sulfotransferase; phenol sulfotransferase; Phenol sulfotransferase 1c1; P-SULT; rabSULT1C2; rSULT1C2; St1c1; ST1C2; ST1C4; Stp2; sulfotransferase; sulfotransferase 1C1; Sulfotransferase 1C2; sulfotransferase 1C4; sulfotransferase family 1A phenol-preferring member 2; sulfotransferase family 1A, member 2; sulfotransferase family 1A, phenol-preferring, member 2; sulfotransferase family 1C member 2; sulfotransferase family 1C member 4; sulfotransferase family, cytosolic, 1C, member 1; sulfotransferase family, cytosolic, 1C, member 2; sulfotransferase family, cytosolic, 1C, member 3; sulfotransferase family, cytosolic, 1C, member 4; sulfotransferase family, cytosolic, 1C, member C2; sulfotransferase K1; sulfotransferase, phenol preferring 2; sulphotransferase family cytosolic 1A phenol-preferring member 2; Sult1a2; SULT1C; SULT1C#1;
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6819
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O00338
Gene Symbols: SULT1C2
Immunogen: Recombinant protein corresponding to Human SULT1C1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SULT1C2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SULT1C2
Gene Alias:
(PST)G; 1810008N17Rik; 1C member 4; HAST-I; humSULTC2; LOC100729651; MGC149521; MGC34422; mOLFST; N-hydroxyarylamine sulfotransferase; N-hydroxylarylamine sulfotransferase; phenol sulfotransferase; Phenol sulfotransferase 1c1; P-SULT; rabSULT1C2; rSULT1C2; St1c1; ST1C2; ST1C4; Stp2; sulfotransferase; sulfotransferase 1C1; Sulfotransferase 1C2; sulfotransferase 1C4; sulfotransferase family 1A phenol-preferring member 2; sulfotransferase family 1A, member 2; sulfotransferase family 1A, phenol-preferring, member 2; sulfotransferase family 1C member 2; sulfotransferase family 1C member 4; sulfotransferase family, cytosolic, 1C, member 1; sulfotransferase family, cytosolic, 1C, member 2; sulfotransferase family, cytosolic, 1C, member 3; sulfotransferase family, cytosolic, 1C, member 4; sulfotransferase family, cytosolic, 1C, member C2; sulfotransferase K1; sulfotransferase, phenol preferring 2; sulphotransferase family cytosolic 1A phenol-preferring member 2; Sult1a2; SULT1C; SULT1C#1;
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6819
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O00338
Gene Symbols:
SULT1C2
Immunogen:
Recombinant protein corresponding to Human SULT1C1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CRCP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CRCP
Gene Alias: AL022669; calcitonin gene-related peptide-receptor component protein; CGRP receptor component; CGRPRCP; CGRP-RCP; CGRP-receptor component protein; Crcp; DNA-directed RNA polymerase III subunit RPC9; RCP; RCP9; RNA polymerase III subunit C9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27297
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O75575
Gene Symbols: CRCP
Immunogen: Recombinant protein corresponding to Human CRCP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CRCP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CRCP
Gene Alias:
AL022669; calcitonin gene-related peptide-receptor component protein; CGRP receptor component; CGRPRCP; CGRP-RCP; CGRP-receptor component protein; Crcp; DNA-directed RNA polymerase III subunit RPC9; RCP; RCP9; RNA polymerase III subunit C9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27297
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O75575
Gene Symbols:
CRCP
Immunogen:
Recombinant protein corresponding to Human CRCP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG