PIPA552558

FRMPD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA552558-Each-of-1 In Stock ₹ 47,015.22

PIPA552558 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

FRMPD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FRMPD4

Gene Alias

FERM and PDZ domain containing 4; FERM and PDZ domain-containing protein 4; FRMPD4; KIAA0195; KIAA0316; PDZ domain-containing protein 10; PDZD10; PDZK10; Preso; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis; TMEM94; Transmembrane protein 94

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9758

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

Lot-Specific

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q14CM0

Gene Symbols

FRMPD4

Immunogen

Recombinant protein corresponding to Human FRMPD4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PETVLFFSGK VEPPHSSHED LTDGLSTRSF CHPEPHERDA LLAGSLNNTL HLSNEQERGD WPGEAPKPPE PYSHHKAHGR SKHPSGSNTQ PGMESDPYEA EDFVCDYHLE ML Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 79%
  • The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain
  • FRMPD4, also known as Preso, also contains another protein interaction domain termed WW (domain with two conserved Trp residues) at its amino terminus
  • It was identified through a yeast two-hybrid screen using the PDZ domain of PSD-95 as bait and is highly expressed in multiple regions of the brain and is enriched in the postsynaptic density (PSD) fractions
  • Overexpression of FRMPD4 in cultured hippocampal neurons significantly increased the linear density of dendritic spines without changing their length and width; conversely, knockdown experiments using RNAi caused a decrease in spine density, indicating FRMPD4 positively regulates dendritic spine density but not morphology
  • The decreased level of FRMPD4 also resulted in reduced levels of excitatory synaptic transmission, suggesting that FRMPD4 is required for maintenance of excitatory synaptic transmission.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA552558

--


Antigen:
FRMPD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FRMPD4

Gene Alias:
FERM and PDZ domain containing 4; FERM and PDZ domain-containing protein 4; FRMPD4; KIAA0195; KIAA0316; PDZ domain-containing protein 10; PDZD10; PDZK10; Preso; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis; TMEM94; Transmembrane protein 94

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9758

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
Lot-Specific

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14CM0

Gene Symbols:
FRMPD4

Immunogen:
Recombinant protein corresponding to Human FRMPD4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552559

--


Antigen:
TCP-1 eta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCT7

Gene Alias:
AA408524; AL022769; CCT7; CCTETA; CCT-eta; CCTH; Cctz; chaperonin containing t-complex polypeptide 1, eta subunit; chaperonin containing t-complex subunit eta; chaperonin containing TCP1 subunit 7; chaperonin containing Tcp1, subunit 7 (eta); chaperonin subunit 7 (eta); HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; NIP7-1; T-complex protein 1 subunit eta; T-complex protein 1 subunit eta, N-terminally processed; TCP1ETA; TCP-1-eta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10574, 12468, 297406

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P80313, Q99832

Gene Symbols:
CCT7

Immunogen:
Recombinant protein corresponding to Human TCP-1 eta

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552560

--


Antigen:
ITGA7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Itga7

Gene Alias:
[a]7; alpha 7A integrin; alpha7; H36-alpha7; integrin alpha 7; integrin alpha 7 chain; integrin alpha-7; Integrin alpha-7 70 kDa form; Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; integrin subunit alpha 7; integrin, alpha 7; ITGA7; UNQ406/PRO768

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3679

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q13683

Gene Symbols:
Itga7

Immunogen:
Recombinant protein corresponding to Human ITGA7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552561

--


Antigen:
CCM2L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccm2l

Gene Alias:
C20orf160; C24H20orf160; CCM2 like scaffold protein; CCM2 like scaffolding protein; Ccm2l; CCM2-like; ccml2; cerebral cavernous malformation 2; cerebral cavernous malformation 2-like; cerebral cavernous malformations 2 protein-like; dJ310O13.5; LOW QUALITY PROTEIN: cerebral cavernous malformations 2 protein-like; RGD1305202; si:dkey-223d9.2; uncharacterized protein C20orf160 homolog; cerebral cavernous malformations 2 protein-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140706

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NUG4

Gene Symbols:
Ccm2l

Immunogen:
Recombinant protein corresponding to Human CCM2L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG