PIPA552617

GRAMD1A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA552617-Each-of-1 In Stock ₹ 47,015.22

PIPA552617 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

GRAMD1A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRAMD1A

Gene Alias

1300003M23Rik; AI415002; AW547240; D7Bwg0611e; GRAM domain containing 1A; GRAM domain-containing protein 1A; GRAMD1A; KIAA1533; Protein Aster-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57655

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96CP6

Gene Symbols

GRAMD1A

Immunogen

Recombinant protein corresponding to Human GRAMD1A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SEDEDYVSPL QLNGLGTPKE VGDVIALSDI TSSGAADRSQ EPSPVGSRRG HVTPNLSRAS SDADHGAEED KEEQVDSQPD ASSSQTVTPV AEPPSTEPTQ PDGPTTLGPL DLLPS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%
  • Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER)
  • Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER
  • Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol
  • In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain
  • At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER
  • May play a role in tumor progression
  • Plays a role in autophagy regulation and is required for biogenesis of the autophagosome (PubMed:31222192)
  • This function in autophagy requires its cholesterol-transfer activity (PubMed:31222192)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA552617

--


Antigen:
GRAMD1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRAMD1A

Gene Alias:
1300003M23Rik; AI415002; AW547240; D7Bwg0611e; GRAM domain containing 1A; GRAM domain-containing protein 1A; GRAMD1A; KIAA1533; Protein Aster-A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57655

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96CP6

Gene Symbols:
GRAMD1A

Immunogen:
Recombinant protein corresponding to Human GRAMD1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA552619

--


Antigen:
FDFT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FDFT1

Gene Alias:
DGPT; EGK_18680; ERG9; farnesyl diphosphate farnesyl transferase 1; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase 1; FDFT1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase; SS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2222

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P37268

Gene Symbols:
FDFT1

Immunogen:
Recombinant protein corresponding to Human FDFT1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA552620

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Antigen:
ADAM7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAM7

Gene Alias:
9230104J12Rik; a disintegrin and metallopeptidase domain 7; a disintegrin and metalloprotease domain (ADAM) 7; a disintegrin and metalloprotease domain 7; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 7; ADAM; ADAM 7; ADAM metallopeptidase domain 7; Adam7; ADAM-7; ADAMs; Disintegrin and metalloproteinase domain-containing protein 7; EAP1; EAPI; epididymal apical protein I; GP83; GP-83; metalloendopeptidases; Sperm maturation-related glycoprotein GP-83

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8756

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H2U9

Gene Symbols:
ADAM7

Immunogen:
Recombinant protein corresponding to Human ADAM7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA552621

--


Antigen:
ME2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Me2

Gene Alias:
AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4200

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P23368

Gene Symbols:
Me2

Immunogen:
Recombinant protein corresponding to Human ME2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG