PIPA552864

Cullin 4B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA552864-Each-of-1 In Stock ₹ 50,309.28

PIPA552864 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

Cullin 4B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CUL4B

Gene Alias

2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

302502, 72584, 8450

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

A2A432, Q13620

Gene Symbols

CUL4B

Immunogen

Recombinant protein corresponding to Human Cullin 4B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GDGNDDEATT SKDGGFSSPS PSAAAAAQEV RSATDGNTST TPPTSAKKRK LNSSSSSSSN SSNEREDFDS TSSSSSTPPL QPRDSASPST SSFCLGVSVA ASSHVPIQKK LRFEDTLEFV GFDAKMAEES SSSSSSSSPT AATS Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%
  • Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Compare Similar Items

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Img

Thermo Scientific

PIPA552864

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Antigen:
Cullin 4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Alias:
2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302502, 72584, 8450

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A2A432, Q13620

Gene Symbols:
CUL4B

Immunogen:
Recombinant protein corresponding to Human Cullin 4B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552865

--


Antigen:
SLC6A18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC6A18

Gene Alias:
b(0)AT3; B0AT3; D630001K16Rik; FLJ31236; Inactive sodium-dependent neutral amino acid transporter B(0)AT3; renal osmotic stress-induced Na-Cl organic solute cotransporter; Rosit; Slc6a18; sodium and chloride dependent transporter Xtrp2; sodium- and chloride-dependent transporter XTRP2; sodium channel-like protein; Sodium-dependent neutral amino acid transporter B(0)AT3; solute carrier family 6 (neurotransmitter transporter), member 18; solute carrier family 6 (neutral amino acid transporter), member 18; solute carrier family 6 member 18; solute carrier family 6, member 18; system B 0 neutral amino acid transporter AT3; system B(0) neutral amino acid transporter AT3; X transporter protein 2; Xt2; Xtrp2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
348932

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96N87

Gene Symbols:
SLC6A18

Immunogen:
Recombinant protein corresponding to Human SLC6A18

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA552866

--


Antigen:
QPRT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
QPRT

Gene Alias:
2410027J01Rik; AI647766; epididymis secretory sperm binding protein Li 90n; HEL-S-90n; nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase (carboxylating); nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; quinolinate phosphoribosyltransferase; Quinolinate phosphoribosyltransferase [decarboxylating]

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23475

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.10 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q15274

Gene Symbols:
QPRT

Immunogen:
Recombinant protein corresponding to Human QPRT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA552867

--


Antigen:
SARG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1orf116

Gene Alias:
AA986860; C1orf116; chromosome 1 open reading frame 116; E030025M07; expressed sequence AA986860; Sarg; Specifically androgen-regulated gene protein; specifically androgen-regulated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79098

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BW04

Gene Symbols:
C1orf116

Immunogen:
Recombinant protein corresponding to Human SARG

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG