PIPA553342

SCNN1B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553342-Each-of-1 In Stock ₹ 47,015.22

PIPA553342 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SCNN1B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCNN1B

Gene Alias

Amiloride-sensitive sodium channel subunit beta; amiloride-sensitive sodium channel subunit beta 1; amiloride-sensitive sodium channel subunit beta-like protein; BESC1; Beta ENaC; beta-ENaC; Beta-NaCH; betaxENaC; ENaC beta; ENaCb; enacbeta; epithelial Na(+) channel subunit beta; epithelial sodium channel beta-2 subunit; epithelial sodium channel beta-3 subunit; epithelial sodium channel, nonvoltage-gated 1, beta; nasal epithelial sodium channel beta subunit; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; SCNN 1B; SCNN1B; scnn1b.L; scnn1b-a; scnn1b-b; sodium channel epithelial 1 beta subunit; sodium channel, non voltage gated 1 beta subunit; sodium channel, non voltage gated 1 beta subunit L homeolog; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated, type I, beta; XELAEV_18045378mg

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6338

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P51168

Gene Symbols

SCNN1B

Immunogen

Recombinant protein corresponding to Human SCNN1B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GIYAMSGTET SIGVLVDKLQ RMGEPYSPCT VNGSEVPVQN FYSDYNTTYS IQACLRSCFQ DHMIRNCNCG HYLYPLPRGE KYCNNRDFPD WAHCYSDLQM SVAQRETCIG MCKESCNDTQ YKMTISMADW PSEASEDWIF HVLS Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%
  • Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride
  • Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells
  • Controls the reabsorption of sodium in kidney, colon, lung and sweat glands
  • Also plays a role in taste perception
  • Heterotetramer of two alpha, one beta and one gamma subunit
  • A delta subunit can replace the alpha subunit
  • Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2
  • Defects in SCNN1B are a cause of autosomal recessive pseudohypoaldosteronism type 1 (PHA1) [MIM:264350]
  • PHA1 is a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids
  • There are 2 forms of PHA1: the autosomal recessive form that is severe, and the dominant form which is more milder and due to defects in mineralocorticoid receptor
  • Autosomal recessive PHA1 is characterized by an often fulminant presentation in the neonatal period with dehydration, hyponatraemia, hyperkalaemia, metabolic acidosis, failure to thrive and weight loss
  • Defects in SCNN1B are a cause of Liddle syndrome
  • It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis
  • The disease is caused by constitutive activation of the renal epithelial sodium channel.

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Show Difference

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Thermo Scientific

PIPA553342

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Antigen:
SCNN1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCNN1B

Gene Alias:
Amiloride-sensitive sodium channel subunit beta; amiloride-sensitive sodium channel subunit beta 1; amiloride-sensitive sodium channel subunit beta-like protein; BESC1; Beta ENaC; beta-ENaC; Beta-NaCH; betaxENaC; ENaC beta; ENaCb; enacbeta; epithelial Na(+) channel subunit beta; epithelial sodium channel beta-2 subunit; epithelial sodium channel beta-3 subunit; epithelial sodium channel, nonvoltage-gated 1, beta; nasal epithelial sodium channel beta subunit; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; SCNN 1B; SCNN1B; scnn1b.L; scnn1b-a; scnn1b-b; sodium channel epithelial 1 beta subunit; sodium channel, non voltage gated 1 beta subunit; sodium channel, non voltage gated 1 beta subunit L homeolog; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated, type I, beta; XELAEV_18045378mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6338

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P51168

Gene Symbols:
SCNN1B

Immunogen:
Recombinant protein corresponding to Human SCNN1B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA553346

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Antigen:
TIMD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TIMD4

Gene Alias:
B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
91937

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96H15

Gene Symbols:
TIMD4

Immunogen:
Recombinant protein corresponding to Human TIMD4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA553347

--


Antigen:
BAP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAIAP3

Gene Alias:
AL031709.1; BAI1 associated protein 3; BAI1-associated protein 3; BAIAP3; BAI-associated protein 3; BAP3; Brain-specific angiogenesis inhibitor I-associated protein 3; Gm937; KIAA0734

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8938

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O94812

Gene Symbols:
BAIAP3

Immunogen:
Recombinant protein corresponding to Human BAP3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA553348

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Antigen:
HERPUD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HERPUD2

Gene Alias:
HERPUD family member 2; HERPUD2; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 2; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64224

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BSE4

Gene Symbols:
HERPUD2

Immunogen:
Recombinant protein corresponding to Human HERPUD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG