PIPA553388

SPEN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553388-Each-of-1 In Stock ₹ 47,443.02

PIPA553388 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

SPEN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPEN

Gene Alias

HIAA0929; KIAA0929; MINT; Msx2 interacting nuclear target (MINT) homolog; msx2-interacting protein; nuclear receptor transcription cofactor; RBM15C; SHARP; SMART/HDAC1-associated repressor protein; SPEN; spen family transcriptional repressor; SPEN homolog; spen homolog, transcriptional regulator

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23013

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.25 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96T58

Gene Symbols

SPEN

Immunogen

Recombinant protein corresponding to Human SPEN

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: NRERAYEHSA YGHHERGTGG FDRTRHYDQD YYRDPRERTL QHGLYYASRS RSPNRFDAHD PRYEPRAREQ FTLPSVVHRD IYRDDITREV RGRRPERNYQ HSRSRSPHSS QSRNQSPQRL ASQASRPTRS PSGSGSRSRS SSSDSI Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%
  • May serve as a nuclear matrix platform that organizes and integrates transcriptional responses
  • In osteoblasts, supports transcription activation: synergizes with RUNX2 to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE)
  • Has also been shown to be an essential corepressor protein, which probably regulates different key pathways such as the Notch pathway
  • Negative regulator of the Notch pathway via its interaction with RBPSUH, which prevents the association between NOTCH1 and RBPSUH, and therefore suppresses the transactivation activity of Notch signaling
  • Blocks the differentiation of precursor B-cells into marginal zone B-cells
  • Probably represses transcription via the recruitment of large complexes containing histone deacetylase proteins
  • May bind both to DNA and RNA.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA553388

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Antigen:
SPEN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPEN

Gene Alias:
HIAA0929; KIAA0929; MINT; Msx2 interacting nuclear target (MINT) homolog; msx2-interacting protein; nuclear receptor transcription cofactor; RBM15C; SHARP; SMART/HDAC1-associated repressor protein; SPEN; spen family transcriptional repressor; SPEN homolog; spen homolog, transcriptional regulator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23013

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.25 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96T58

Gene Symbols:
SPEN

Immunogen:
Recombinant protein corresponding to Human SPEN

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553389

--


Antigen:
RBBP9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBBP9

Gene Alias:
B5T overexpressed gene protein; B5T-overexpressed gene protein; BOG; im:7247963; im:7247963 protein; MGC9236; Protein BOG; Putative hydrolase RBBP9; RB binding protein 9, serine hydrolase; RBBP10; RBBP-10; Rbbp9; RBBP-9; retinoblastoma binding protein 9; retinoblastoma-binding protein 10; Retinoblastoma-binding protein 9; retinoma-binding protein 9; serine hydrolase RBBP9; serine hydrolase RBBP9; putative hydrolase RBBP9; si:ch211-258l4.7; zgc:152807

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10741

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O75884

Gene Symbols:
RBBP9

Immunogen:
Recombinant protein corresponding to Human RBBP9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553392

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Antigen:
PCLO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCLO

Gene Alias:
Acz; Aczonin; brain-derived HLMN protein; KIAA0559; LOW QUALITY PROTEIN: protein piccolo; multidomain presynaptic cytomatrix protein; multidomain presynaptic cytomatrix protein Piccolo; PCH3; PCLO; piccolo (presynaptic cytomatrix protein); piccolo presynaptic cytomatrix protein; Pico; presynaptic cytomatrix protein; protein piccolo

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27445

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.30 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9Y6V0

Gene Symbols:
PCLO

Immunogen:
Recombinant protein corresponding to Human PCLO

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553394

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Antigen:
TMEM45B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM45B

Gene Alias:
TMEM45B; Transmembrane protein 45B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
120224

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96B21

Gene Symbols:
TMEM45B

Immunogen:
Recombinant protein corresponding to Human TMEM45B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG