PIPA553848

GCN1L1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA553848-Each-of-1 In Stock ₹ 51,336.00

PIPA553848 - Each of 1

₹ 51,336.00

In Stock

Quantity

1

Base Price: ₹ 51,336.00

GST (18%): ₹ 9,240.48

Total Price: ₹ 60,576.48

Antigen

GCN1L1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GCN1

Gene Alias

4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; Gcn1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; hsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; translational activator GCN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10985

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q92616

Gene Symbols

GCN1

Immunogen

Recombinant protein corresponding to Human GCN1L1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: EALVTDAGEV TEAGKAYVPP RVLQEALCVI SGVPGLKGDV TDTEQLAQEM LIISHHPSLV AVQSGLWPAL LARMKIDPEA FITRHLDQII PRMTTQSPLN QSSMNAMGSL SVLSPDRVLP QLISTITA Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%
  • Acts as a positive activator of the EIF2AK4/GCN2 protein kinase activity in response to amino acid starvation
  • Forms a complex with EIF2AK4/GCN2 on translating ribosomes; during this process, GCN1 seems to act as a chaperone to facilitate delivery of uncharged tRNAs that enter the A site of ribosomes to the tRNA-binding domain of EIF2AK4/GCN2, and hence stimulating EIF2AK4/GCN2 kinase activity
  • Participates in the repression of global protein synthesis and in gene-specific mRNA translation activation, such as the transcriptional activator ATF4, by promoting the EIF2AK4/GCN2-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52', and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion
  • [UniProt]

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Thermo Scientific

PIPA553848

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Antigen:
GCN1L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCN1

Gene Alias:
4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; Gcn1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; hsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; translational activator GCN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10985

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q92616

Gene Symbols:
GCN1

Immunogen:
Recombinant protein corresponding to Human GCN1L1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553850

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Antigen:
NLE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NLE1

Gene Alias:
AL022765; BC018399; FLJ10458; HUSSY-07; l11Jus1; l11Jus4; Nle; Nle1; Notchless gene homolog; notchless homolog 1; notchless homolog 1 (Drosophila); notchless protein homolog 1; novel WD40 repeat containing protein; RGD1308301

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54475

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NVX2

Gene Symbols:
NLE1

Immunogen:
Recombinant protein corresponding to Human NLE1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553851

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Antigen:
SLC43A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC43A1

Gene Alias:
2610016F07Rik; AA986141; large neutral amino acids transporter small subunit 3; LAT3; L-type amino acid transporter 3; PB39; POV1; prostate cancer overexpressed gene 1; prostate cancer overexpressed gene 1 protein; R00504; Slc43a1; solute carrier family 43 (amino acid system L transporter), member 1; solute carrier family 43 member 1; solute carrier family 43, member 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8501

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O75387

Gene Symbols:
SLC43A1

Immunogen:
Recombinant protein corresponding to Human SLC43A1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553852

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Antigen:
TXNDC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TXNDC2

Gene Alias:
spermatid-specific thioredoxin-1; sperm-specific thioredoxin 1; SPTRX; SPTRX1; Sptrx-1; testicular tissue protein Li 215; thioredoxin domain containing 2; thioredoxin domain containing 2 (spermatozoa); thioredoxin domain-containing 2 (spermatozoa); thioredoxin domain-containing protein 2; TXNDC2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84203

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86VQ3

Gene Symbols:
TXNDC2

Immunogen:
Recombinant protein corresponding to Human TXNDC2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG