PIPA554247
ZCCHC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA554247-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA554247 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
ZCCHC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZCCHC6
Gene Alias
6030448M23Rik; AA420405; FLJ13409; HS2; KIAA1711; PAP associated domain containing 6; PAPD6; Terminal uridylyltransferase 7; TUT7; TUTase 7; TUTase7; Zcchc6; Zinc finger CCHC domain-containing protein 6; zinc finger CCHC-type containing 6; zinc finger, CCHC domain containing 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
79670
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q5VYS8
Gene Symbols
ZCCHC6
Immunogen
Recombinant protein corresponding to Human ZCCHC6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DDYKGDKVYH PETGRKNEKE KVGRKGKHLL TVDQKRGEHV VCGSTRNNES ESTLDLEGFQ NPTAKECEGL ATLDNKADLD GESTEGTEEL EDSLNHFTHS VQGQ Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 37%
- Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay (PubMed:19703396, PubMed:25480299)
- Essential for both oocyte maturation and fertility
- Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth
- Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets (PubMed:25480299)
- Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms (PubMed:25979828)
- Acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7)
- Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation
- Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A (PubMed:22898984)
- In the absence of LIN28A, TUT7 and TUT4 monouridylate group II pre-miRNAs, which includes most of pre-let7 members, that shapes an optimal 3' end overhang for efficient processing (PubMed:25979828, PubMed:28671666)
- Add oligo-U tails to truncated pre-miRNAS with a 5' overhang which may promote rapid degradation of non-functional pre-miRNA species (PubMed:25979828)
- Does not play a role in replication-dependent histone mRNA degradation (PubMed:18172165)
- Due to functional redundancy between TUT4 and TUT7, the identification of the specific role of each of these proteins is difficult (PubMed:25979828, PubMed:25480299, PubMed:19703396, PubMed:22898984, PubMed:18172165, PubMed:28671666)
- TUT4 and TUT7 restrict retrotransposition of long interspersed element-1 (LINE-1) in cooperation with MOV10 counteracting the RNA chaperonne activity of L1RE1
- TUT7 uridylates LINE-1 mRNAs in the cytoplasm which inhibits initiation of reverse transcription once in the nucleus, whereas uridylation by TUT4 destabilizes mRNAs in cytoplasmic ribonucleoprotein granules (PubMed:30122351)
- [UniProt]
Compare Similar Items
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Antigen: ZCCHC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZCCHC6
Gene Alias: 6030448M23Rik; AA420405; FLJ13409; HS2; KIAA1711; PAP associated domain containing 6; PAPD6; Terminal uridylyltransferase 7; TUT7; TUTase 7; TUTase7; Zcchc6; Zinc finger CCHC domain-containing protein 6; zinc finger CCHC-type containing 6; zinc finger, CCHC domain containing 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79670
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5VYS8
Gene Symbols: ZCCHC6
Immunogen: Recombinant protein corresponding to Human ZCCHC6
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZCCHC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZCCHC6
Gene Alias:
6030448M23Rik; AA420405; FLJ13409; HS2; KIAA1711; PAP associated domain containing 6; PAPD6; Terminal uridylyltransferase 7; TUT7; TUTase 7; TUTase7; Zcchc6; Zinc finger CCHC domain-containing protein 6; zinc finger CCHC-type containing 6; zinc finger, CCHC domain containing 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79670
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5VYS8
Gene Symbols:
ZCCHC6
Immunogen:
Recombinant protein corresponding to Human ZCCHC6
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C9orf126
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SCAI
Gene Alias: 9330112M16; A930041I02Rik; AI662729; C9orf126; NET40; protein SCAI; SCAI; suppressor of cancer cell invasion; suppressor of cancer cell invasion protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 286205
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N9R8
Gene Symbols: SCAI
Immunogen: Recombinant protein corresponding to Human C9orf126
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C9orf126
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SCAI
Gene Alias:
9330112M16; A930041I02Rik; AI662729; C9orf126; NET40; protein SCAI; SCAI; suppressor of cancer cell invasion; suppressor of cancer cell invasion protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
286205
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N9R8
Gene Symbols:
SCAI
Immunogen:
Recombinant protein corresponding to Human C9orf126
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AASS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AASS
Gene Alias: AASS; aass {ECO:0000312; alpha-aminoadipate semialdehyde synthase; alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; EMBL:AAI28772.1}; LKR; LKR/SDH; LKRSDH; LOR; LOR/SDH; Lorsdh; Lysine ketoglutarate reductase; lysine oxoglutarate reductase; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; saccharopine dehydrogenase; SDH
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10157
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9UDR5
Gene Symbols: AASS
Immunogen: Recombinant protein corresponding to Human AASS
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
AASS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AASS
Gene Alias:
AASS; aass {ECO:0000312; alpha-aminoadipate semialdehyde synthase; alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; EMBL:AAI28772.1}; LKR; LKR/SDH; LKRSDH; LOR; LOR/SDH; Lorsdh; Lysine ketoglutarate reductase; lysine oxoglutarate reductase; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; saccharopine dehydrogenase; SDH
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10157
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9UDR5
Gene Symbols:
AASS
Immunogen:
Recombinant protein corresponding to Human AASS
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PRPF4B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRPF4B
Gene Alias: 2610037H07; cbp143; dJ1013A10.1; dJ1013A10.1 (PRP4 protein kinase homolog); KIAA0536; PR4H; pre-mRNA processing factor 4B; pre-mRNA protein kinase; protein-serine/threonine kinase; Prp4; PRP4 kinase; PRP4 pre-mRNA processing factor 4 homolog B; PRP4 pre-mRNA processing factor 4 homolog B (yeast); PRP4 pre-mRNA-processing factor 4 homolog; PRP4H; PRP4K; Prp4m; Prpf4b; Prpk; RP5-1013A10.2; Serine/threonine-protein kinase PRP4 homolog
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8899
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.15 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q13523
Gene Symbols: PRPF4B
Immunogen: Recombinant protein corresponding to Human PRPF4B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PRPF4B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRPF4B
Gene Alias:
2610037H07; cbp143; dJ1013A10.1; dJ1013A10.1 (PRP4 protein kinase homolog); KIAA0536; PR4H; pre-mRNA processing factor 4B; pre-mRNA protein kinase; protein-serine/threonine kinase; Prp4; PRP4 kinase; PRP4 pre-mRNA processing factor 4 homolog B; PRP4 pre-mRNA processing factor 4 homolog B (yeast); PRP4 pre-mRNA-processing factor 4 homolog; PRP4H; PRP4K; Prp4m; Prpf4b; Prpk; RP5-1013A10.2; Serine/threonine-protein kinase PRP4 homolog
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8899
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.15 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q13523
Gene Symbols:
PRPF4B
Immunogen:
Recombinant protein corresponding to Human PRPF4B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG