PIPA554670
SLFN11 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA554670-Each-of-1 | In Stock | ₹ 50,480.40 |
PIPA554670 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
SLFN11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLFN11
Gene Alias
schlafen family member 11; SLFN11; SLFN8/9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
91607
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q7Z7L1
Gene Symbols
SLFN11
Immunogen
Recombinant protein corresponding to Human SLFN11
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: REVLGCAKEN VDPDSLRRKI EQAIYKLPCV HFCQPQRPIT FTLKIVDVLK RGELYGYACM IRVNPFCCAV FSEAPNSWI Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 53%
- Inhibitor of DNA replication that promotes cell death in response to DNA damage (PubMed:22927417, PubMed:26658330, PubMed:29395061)
- Acts as a guardian of the genome by killing cells with defective replication (PubMed:29395061)
- Persistently blocks stressed replication forks by opening chromatin across replication initiation sites at stressed replication forks, possibly leading to unwind DNA ahead of the MCM helicase and block fork progression, μgtimately leading to cell death (PubMed:29395061)
- Acts independently of ATR (PubMed:29395061)
- Also acts as an interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis (PubMed:23000900)
- Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner (PubMed:23000900)
- Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides (PubMed:23000900)
- The exact inhibition mechanism is unclear: may either sequester tRNAs, prevent their maturation via post-transcriptional processing or may accelerate their deacylation (PubMed:23000900)
- Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA (PubMed:23000900)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: SLFN11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLFN11
Gene Alias: schlafen family member 11; SLFN11; SLFN8/9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 91607
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q7Z7L1
Gene Symbols: SLFN11
Immunogen: Recombinant protein corresponding to Human SLFN11
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SLFN11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLFN11
Gene Alias:
schlafen family member 11; SLFN11; SLFN8/9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
91607
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q7Z7L1
Gene Symbols:
SLFN11
Immunogen:
Recombinant protein corresponding to Human SLFN11
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RNMTL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MRM3
Gene Alias: 16S rRNA (guanosine(1370)-2'-O)-methyltransferase; 16S rRNA [Gm1370] 2'-O-methyltransferase; 4833420N02Rik; AI255153; HC90; mitochondrial rRNA methyltransferase 3; MRM3; putative RNA methyltransferase; RGD1309077; RMTL1; RNA methyltransferase like 1; RNA methyltransferase-like protein 1; RNMTL1; rRNA methyltransferase 3, mitochondrial
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55178
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9HC36
Gene Symbols: MRM3
Immunogen: Recombinant protein corresponding to Human RNMTL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RNMTL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MRM3
Gene Alias:
16S rRNA (guanosine(1370)-2'-O)-methyltransferase; 16S rRNA [Gm1370] 2'-O-methyltransferase; 4833420N02Rik; AI255153; HC90; mitochondrial rRNA methyltransferase 3; MRM3; putative RNA methyltransferase; RGD1309077; RMTL1; RNA methyltransferase like 1; RNA methyltransferase-like protein 1; RNMTL1; rRNA methyltransferase 3, mitochondrial
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55178
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9HC36
Gene Symbols:
MRM3
Immunogen:
Recombinant protein corresponding to Human RNMTL1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C17orf58
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C17orf58
Gene Alias: C17orf58; chromosome 17 open reading frame 58; UPF0450 protein C17orf58
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 284018
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.5 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q2M2W7
Gene Symbols: C17orf58
Immunogen: Recombinant protein corresponding to Human C17orf58
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C17orf58
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C17orf58
Gene Alias:
C17orf58; chromosome 17 open reading frame 58; UPF0450 protein C17orf58
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
284018
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.5 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q2M2W7
Gene Symbols:
C17orf58
Immunogen:
Recombinant protein corresponding to Human C17orf58
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VMO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vmo1
Gene Alias: ERGA6350; ERGA6350 antibody; Gm741; MGC125880 antibody; MGC125881 antibody; PRO21055; PRO21055 antibody; RGD1559861; UNQ6350/PRO21055; vitelline membrane outer layer 1 homolog; vitelline membrane outer layer 1 homolog (chicken); vitelline membrane outer layer 1 homolog (chicken) antibody; vitelline membrane outer layer protein 1 homolog; vitelline membrane outer layer protein 1 homolog antibody; VMO1; VMO1 antibody
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 284013
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q7Z5L0
Gene Symbols: Vmo1
Immunogen: Recombinant protein corresponding to Human VMO1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
VMO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vmo1
Gene Alias:
ERGA6350; ERGA6350 antibody; Gm741; MGC125880 antibody; MGC125881 antibody; PRO21055; PRO21055 antibody; RGD1559861; UNQ6350/PRO21055; vitelline membrane outer layer 1 homolog; vitelline membrane outer layer 1 homolog (chicken); vitelline membrane outer layer 1 homolog (chicken) antibody; vitelline membrane outer layer protein 1 homolog; vitelline membrane outer layer protein 1 homolog antibody; VMO1; VMO1 antibody
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
284013
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q7Z5L0
Gene Symbols:
Vmo1
Immunogen:
Recombinant protein corresponding to Human VMO1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG