PIPA554718
NISCH Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA554718-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA554718 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
NISCH
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NISCH
Gene Alias
1200007D05Rik; 3202002H23Rik; AW494485; hIRAS; I-1; I-1 receptor candidate protein; I1R; I1R candidate protein; imidazoline receptor 1; imidazoline receptor antisera selected; Imidazoline receptor antisera-selected protein; imidazoline receptor I-1; imidazoline receptor I-1-like protein; Imidazoline-1 receptor; Imidazoline-1 receptor candidate protein; IR1; IRAS; KIAA0975; NISCH; Nischarin
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11188
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9Y2I1
Gene Symbols
NISCH
Immunogen
Recombinant protein corresponding to Human NISCH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AHFLHFHFYE INGITAALAE ELFEKGEQLL GAGEVFAIGP LQLYAVTEQL QQGKPTCASG DAKTDLGHIL DFTCRLKYLK VSGTEGPFGT SNIQEQLLPF DLSIFKSLHQ VEISHCDAKH IRGLVASKPT LATLSVRFSA TSMKEV Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%
- Acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling
- Binds numerous imidazoline ligands that induces initiation of cell-signaling cascades triggering to cell survival, growth and migration
- Its activation by the agonist rilmenidine induces an increase in phosphorylation of mitogen-activated protein kinases MAPK1 and MAPK3 in rostral ventrolateral medulla (RVLM) neurons that exhibited rilmenidine-evoked hypotension
- Blocking its activation with efaroxan abolished rilmenidine-induced mitogen-activated protein kinase phosphorylation in RVLM neurons
- Acts as a modulator of Rac-regulated signal transduction pathways
- Suppresses Rac1-stimulated cell migration by interacting with PAK1 and inhibiting its kinase activity
- Also blocks Pak-independent Rac signaling by interacting with RAC1 and inhibiting Rac1-stimulated NF-kB response element and cyclin D1 promoter activation
- Inhibits also LIMK1 kinase activity by reducing LIMK1 'Tyr-508' phosphorylation
- Inhibits Rac-induced cell migration and invasion in breast and colon epithelial cells
- Inhibits lamellipodia formation, when overexpressed
- Plays a role in protection against apoptosis
- Involved in association with IRS4 in the enhancement of insulin activation of MAPK1 and MAPK3
- When overexpressed, induces a redistribution of cell surface ITGA5 integrin to intracellular endosomal structures.
Compare Similar Items
Show Difference
Antigen: NISCH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NISCH
Gene Alias: 1200007D05Rik; 3202002H23Rik; AW494485; hIRAS; I-1; I-1 receptor candidate protein; I1R; I1R candidate protein; imidazoline receptor 1; imidazoline receptor antisera selected; Imidazoline receptor antisera-selected protein; imidazoline receptor I-1; imidazoline receptor I-1-like protein; Imidazoline-1 receptor; Imidazoline-1 receptor candidate protein; IR1; IRAS; KIAA0975; NISCH; Nischarin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11188
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9Y2I1
Gene Symbols: NISCH
Immunogen: Recombinant protein corresponding to Human NISCH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NISCH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NISCH
Gene Alias:
1200007D05Rik; 3202002H23Rik; AW494485; hIRAS; I-1; I-1 receptor candidate protein; I1R; I1R candidate protein; imidazoline receptor 1; imidazoline receptor antisera selected; Imidazoline receptor antisera-selected protein; imidazoline receptor I-1; imidazoline receptor I-1-like protein; Imidazoline-1 receptor; Imidazoline-1 receptor candidate protein; IR1; IRAS; KIAA0975; NISCH; Nischarin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11188
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9Y2I1
Gene Symbols:
NISCH
Immunogen:
Recombinant protein corresponding to Human NISCH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF574
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF574
Gene Alias: FP972; Zinc finger protein 574; ZNF574
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64763
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6ZN55
Gene Symbols: ZNF574
Immunogen: Recombinant protein corresponding to Human ZNF574
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF574
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF574
Gene Alias:
FP972; Zinc finger protein 574; ZNF574
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64763
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6ZN55
Gene Symbols:
ZNF574
Immunogen:
Recombinant protein corresponding to Human ZNF574
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FMNL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FMNL3
Gene Alias: 2700073B04Rik; FBP11; FHOD3; FMNL3; Formin homology 2 domain-containing protein 3; formin like 3; formin-like 3; formin-like 3 protein; formin-like protein 3; Frl2; KIAA2014; mKIAA2014; WBP3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 91010
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IVF7
Gene Symbols: FMNL3
Immunogen: Recombinant protein corresponding to Human FMNL3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FMNL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FMNL3
Gene Alias:
2700073B04Rik; FBP11; FHOD3; FMNL3; Formin homology 2 domain-containing protein 3; formin like 3; formin-like 3; formin-like 3 protein; formin-like protein 3; Frl2; KIAA2014; mKIAA2014; WBP3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
91010
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IVF7
Gene Symbols:
FMNL3
Immunogen:
Recombinant protein corresponding to Human FMNL3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: POLG2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLG2
Gene Alias: AA409516; DNA polymerase gamma; DNA polymerase gamma 2, accessory subunit; DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha); DNA polymerase gamma, catalytic subunit; DNA polymerase subunit gamma-1; DNA polymerase subunit gamma-2, mitochondrial; DNA-directed DNA polymerase gamma; HP55; MDP1; Mip1; MIRAS; Mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase catalytic subunit; mitochondrial DNA polymerase gamma; mitochondrial DNA polymerase gamma catalytic subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; mitochondrial DNA polymerase-gamma; mitochondrial polymerase gamma; mitochondrial polymerase gamma 2; MTDPS4A; MTDPS4B; MTPOLB; p55; PEO; PEOA4; Pol gamma; POLB; POLG; POLG1; Polg2; POLGA; PolG-alpha; POLGB; polG-beta; polymerase (DNA directed), gamma; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9UHN1
Gene Symbols: POLG2
Immunogen: Recombinant protein corresponding to Human POLG2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
POLG2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLG2
Gene Alias:
AA409516; DNA polymerase gamma; DNA polymerase gamma 2, accessory subunit; DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha); DNA polymerase gamma, catalytic subunit; DNA polymerase subunit gamma-1; DNA polymerase subunit gamma-2, mitochondrial; DNA-directed DNA polymerase gamma; HP55; MDP1; Mip1; MIRAS; Mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase catalytic subunit; mitochondrial DNA polymerase gamma; mitochondrial DNA polymerase gamma catalytic subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; mitochondrial DNA polymerase-gamma; mitochondrial polymerase gamma; mitochondrial polymerase gamma 2; MTDPS4A; MTDPS4B; MTPOLB; p55; PEO; PEOA4; Pol gamma; POLB; POLG; POLG1; Polg2; POLGA; PolG-alpha; POLGB; polG-beta; polymerase (DNA directed), gamma; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9UHN1
Gene Symbols:
POLG2
Immunogen:
Recombinant protein corresponding to Human POLG2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG