PIPA555064

GCN1L1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555064-Each-of-1 In Stock ₹ 50,309.28

PIPA555064 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

GCN1L1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GCN1

Gene Alias

4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; Gcn1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; hsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; translational activator GCN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10985

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q92616

Gene Symbols

GCN1

Immunogen

Recombinant protein corresponding to Human GCN1L1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LLPLLIQTVE KAASQSTQVP TITEGVAAAL LLLKLSVADS QAEAKLSSFW QLIVDEKKQV FTSEKFLVMA SEDALCTVLH LTERLFLDHP HRLTGNKVQQ YHRALVAVLL SRTWHVRRQA QQTVRKLLSS L Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%
  • Acts as a positive activator of the EIF2AK4/GCN2 protein kinase activity in response to amino acid starvation
  • Forms a complex with EIF2AK4/GCN2 on translating ribosomes; during this process, GCN1 seems to act as a chaperone to facilitate delivery of uncharged tRNAs that enter the A site of ribosomes to the tRNA-binding domain of EIF2AK4/GCN2, and hence stimulating EIF2AK4/GCN2 kinase activity
  • Participates in the repression of global protein synthesis and in gene-specific mRNA translation activation, such as the transcriptional activator ATF4, by promoting the EIF2AK4/GCN2-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52', and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion
  • [UniProt]

Compare Similar Items

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Thermo Scientific

PIPA555064

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Antigen:
GCN1L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCN1

Gene Alias:
4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; Gcn1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; hsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; translational activator GCN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10985

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q92616

Gene Symbols:
GCN1

Immunogen:
Recombinant protein corresponding to Human GCN1L1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA555065

--


Antigen:
GATAD2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GATAD2A

Gene Alias:
1110066C11Rik; BC031407; C80248; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66alpha; MGC29315; MGC36975; p66 alpha; p66a; p66alpha; RGD1310596; transcriptional repressor p66 alpha; Transcriptional repressor p66-alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54815

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86YP4

Gene Symbols:
GATAD2A

Immunogen:
Recombinant protein corresponding to Human GATAD2A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555071

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Antigen:
C16orf58

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C16orf58

Gene Alias:
C16orf58; chromosome 16 open reading frame 58; RUS; RUS1 family protein C16orf58; UPF0420 protein C16orf58

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64755

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96GQ5

Gene Symbols:
C16orf58

Immunogen:
Recombinant protein corresponding to Human C16orf58

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555072

--


Antigen:
LURAP1L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LURAP1L

Gene Alias:
1110029A09Rik; amplimer WI-13707, mouse homolog; AV077978; AV175137; bA3L8.2; bM350F23.1; C9orf150; ci150; D4Bwg0951e; HYST0841; leucine repeat adaptor protein 35b; leucine rich adaptor protein 1 like; leucine rich adaptor protein 1-like; LRAP35b; LURAP1L; RGD1308059; WI-13707

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
286343

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IV03

Gene Symbols:
LURAP1L

Immunogen:
Recombinant protein corresponding to Human LURAP1L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG