PIPA555203

PLEKHM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA555203-Each-of-1 In Stock ₹ 47,015.22

PIPA555203 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

PLEKHM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLEKHM1

Gene Alias

162 kDa adapter protein; AP162; B2; BC038943; D330036J23Rik; KIAA0356; OPTB6; PH domain-containing family M member 1; pleckstrin homology and RUN domain containing M1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1; PLEKHM1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9842

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9Y4G2

Gene Symbols

PLEKHM1

Immunogen

Recombinant protein corresponding to Human PLEKHM1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LTASSLSLDT ASSSQLSCSL NSDSCLLQEN GSKSPDHCEE PMSCDSDLGT ANAEDSDRSL QEVLLEFSKA QVNSVPTNGL SQETEIPTPQ ASLSLHGLNT STYLHCEAP Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%
  • PLEKHM1 is a member of the M family of Pleckstrin homolog domain-containing proteins, a group of proteins containing a RUN domain, two pleckstrin homology domains, and a cysteine-rich domain
  • It was identified through segregation analysis as a cause of osteopetrosis in humans
  • PLEKHM1 co-localizes with Rab7 to late endosomal/lysosomal vesicles in HEK293 and osteoclast-like cells, with this co-localization dependent on the prenylation of Rab7
  • Monocytes from a patient homozygous for a mutated form of PLEKHM1differentiated into osteoclasts normally, but failed to form ruffled borders and showed little evidence of bone resorption when cultured on dentine discs
  • Another mutation of PLEKHM1 impaired vesicular acidification and increased TRACP secretion in osteoclasts, suggesting that PLEKHM1 has critical roles in endosomal maturation and may be important in osteoclast-osteoblast cross-talk.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA555203

--


Antigen:
PLEKHM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLEKHM1

Gene Alias:
162 kDa adapter protein; AP162; B2; BC038943; D330036J23Rik; KIAA0356; OPTB6; PH domain-containing family M member 1; pleckstrin homology and RUN domain containing M1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1; PLEKHM1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9842

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9Y4G2

Gene Symbols:
PLEKHM1

Immunogen:
Recombinant protein corresponding to Human PLEKHM1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555205

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Antigen:
TMEM65

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM65

Gene Alias:
2610029O13Rik; 4930438D12Rik; TMEM65; Transmembrane protein 65

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
157378

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
0.10 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6PI78

Gene Symbols:
TMEM65

Immunogen:
Recombinant protein corresponding to Human TMEM65

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555206

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Antigen:
BTBD17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BTBD17

Gene Alias:
1500005I02Rik; BTB (POZ) domain containing 17; BTB domain containing 17; BTB/POZ and BACK domain-containing protein LOC388419; BTB/POZ domain-containing protein 17; Btbd17; BTBD17A; Galectin-3-binding protein-like; LGALS3BPL; RGD1563331; TANGO10A; transport and golgi organization 10 homolog A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
388419

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A6NE02

Gene Symbols:
BTBD17

Immunogen:
Recombinant protein corresponding to Human BTBD17

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555207

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Antigen:
KIF13B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF13B

Gene Alias:
5330429L19Rik; 6030414C01; AI429803; C130021D12Rik; GAKIN; guanylate kinase associated kinesin; KIAA0639; Kif13b; kinesin 13B; kinesin family member 13B; kinesin-like protein GAKIN; Kinesin-like protein KIF13B; N-3 kinesin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23303

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NQT8

Gene Symbols:
KIF13B

Immunogen:
Recombinant protein corresponding to Human KIF13B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG