PIPA555495

OTUD7B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555495-Each-of-1 In Stock ₹ 47,015.22

PIPA555495 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

OTUD7B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OTUD7B

Gene Alias

2900060B22Rik; 4930463P07Rik; AI462125; cellular zinc finger anti-NF-kappaB Cezanne; cellular zinc finger anti-NF-kappa-B protein; CEZANNE; OTU deubiquitinase 7B; OTU domain containing 7B; OTU domain-containing protein 7B; OTUD7B; RGD1308111; Trabid2; TRAF binding domain containing 2; Za20d1; Zinc finger A20 domain-containing protein 1; zinc finger protein Cezanne; zinc finger, A20 domain containing 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56957

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6GQQ9

Gene Symbols

OTUD7B

Immunogen

Recombinant protein corresponding to Human OTUD7B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PHQDSIPSLE PGSHSKDGLH RGALLPPPYR VADSYSNGYR EPPEPDGWAG GLRGLPPTQT KCKQPNCSFY G Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%
  • Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses
  • In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B
  • Negatively regulates mucosal immunity against infections
  • Deubiquitinates ZAP70, and thereby regulates T cell receptor (TCR) signaling that leads to the activation of NF-kappa-B (PubMed:26903241)
  • Plays a role in T cell homeostasis and is required for normal T cell responses, including production of IFNG and IL2
  • Mediates deubiquitination of EGFR (PubMed:22179831)
  • Has deubiquitinating activity toward 'Lys-11', 'Lys-48' and 'Lys-63'-linked polyubiquitin chains (PubMed:27732584)
  • Has a much higher catalytic rate with 'Lys-11'-linked polyubiquitin chains (in vitro); however the physiological significance of these data are unsure (PubMed:27732584)
  • Hydrolyzes both linear and branched forms of polyubiquitin
  • [UniProt]

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Show Difference

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PIPA555495

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Antigen:
OTUD7B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OTUD7B

Gene Alias:
2900060B22Rik; 4930463P07Rik; AI462125; cellular zinc finger anti-NF-kappaB Cezanne; cellular zinc finger anti-NF-kappa-B protein; CEZANNE; OTU deubiquitinase 7B; OTU domain containing 7B; OTU domain-containing protein 7B; OTUD7B; RGD1308111; Trabid2; TRAF binding domain containing 2; Za20d1; Zinc finger A20 domain-containing protein 1; zinc finger protein Cezanne; zinc finger, A20 domain containing 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56957

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6GQQ9

Gene Symbols:
OTUD7B

Immunogen:
Recombinant protein corresponding to Human OTUD7B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555496

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Antigen:
TMEM199

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM199

Gene Alias:
AI316787; AI848469; C17orf32; CDG2P; hypothetical protein LOC553562; R74819; RE40914p; TMEM199; Transmembrane protein 199; Unknown (protein for MGC:137613); VMA12; VPH2; zgc:109974

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147007, 195040, 303332

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5BK13, Q5SYH2, Q8N511

Gene Symbols:
TMEM199

Immunogen:
Recombinant protein corresponding to Human TMEM199

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA555500

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Antigen:
TTLL4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TTLL4

Gene Alias:
KIAA0173; TTLL4; Tubulin polyglutamylase TTLL4; tubulin tyrosine ligase like 4; tubulin tyrosine ligase-like family member 4; tubulin tyrosine ligase-like family, member 4; tubulin--tyrosine ligase-like protein 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14679

Gene Symbols:
TTLL4

Immunogen:
Recombinant protein corresponding to Human TTLL4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555501

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Antigen:
SIGLEC10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIGLEC10

Gene Alias:
PRO940; sialic acid binding Ig like lectin 10; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Siglec; SIGLEC10; Siglec-10; Siglecg; siglec-like gene 2; siglec-like protein 2; SLG2; UNQ477/PRO940

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.14 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96LC7

Gene Symbols:
SIGLEC10

Immunogen:
Recombinant protein corresponding to Human SIGLEC10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG