PIPA555750

DTL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555750-Each-of-1 In Stock ₹ 47,015.22

PIPA555750 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

DTL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DTL

Gene Alias

2810047L02Rik; 5730564G15Rik; CDT2; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; DDB1- and CUL4-associated factor 2; denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; DTL; L2dtl; lethal(2) denticleless protein homolog; Meth A RAMP; Meth A retinoic acid-regulated nuclear matrix-associated protein; RA regulated nuclear matrix associated protein; RAMP; RA-regulated nuclear matrix-associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RGD1310439

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51514

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NZJ0

Gene Symbols

DTL

Immunogen

Recombinant protein corresponding to Human DTL

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: TVVLFQDENT LVSAGAVDGI IKVWDLRKNY TAYRQEPIAS KSFLYPGSST RKLGYSSLIL DSTGSTLFAN CTDDNIYMFN MTGLKTSPVA IF Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 95%
  • Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis
  • The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1)
  • CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication
  • CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing
  • Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation
  • In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA555750

--


Antigen:
DTL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DTL

Gene Alias:
2810047L02Rik; 5730564G15Rik; CDT2; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; DDB1- and CUL4-associated factor 2; denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; DTL; L2dtl; lethal(2) denticleless protein homolog; Meth A RAMP; Meth A retinoic acid-regulated nuclear matrix-associated protein; RA regulated nuclear matrix associated protein; RAMP; RA-regulated nuclear matrix-associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RGD1310439

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51514

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NZJ0

Gene Symbols:
DTL

Immunogen:
Recombinant protein corresponding to Human DTL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555751

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Antigen:
ODF2L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Odf2l

Gene Alias:
4733401D09Rik; 9630045K08Rik; Basal body centriole-associated protein; Bcap; D3Ertd250e; dJ977L11.1; KIAA1229; ODF2L; outer dense fiber of sperm tails 2 like; outer dense fiber of sperm tails 2-like; outer dense fiber protein 2-like; Protein BCAP; RGD1308397

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57489

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9ULJ1

Gene Symbols:
Odf2l

Immunogen:
Recombinant protein corresponding to Human ODF2L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555754

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Antigen:
DHX9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dhx9

Gene Alias:
AI326842; ATP-dependent RNA helicase A; Ddx9; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 9; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 9; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9; DEAH (Asp-Glu-Ala-His) box helicase 9; DEAH (Asp-Glu-Ala-His) box polypeptide 9; DEAH box protein 9; DEAH-box helicase 9; DExH-box helicase 9; Dhx9; FLJ17406; HEL-5; Leukophysin; LKP; mHEL-5; NDH II; NDH2; NDHII; Nuclear DNA helicase II; OTTHUMP00000033287; RHA; RNA helicase; RNA helicase A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13211, 1660, 304859

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O70133, Q08211

Gene Symbols:
Dhx9

Immunogen:
Recombinant protein corresponding to Human DHX9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA555755

--


Antigen:
LYSMD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYSMD1

Gene Alias:
2610022K04Rik; AI415311; lysM and putative peptidoglycan-binding domain-containing protein 1; LysM domain containing 1; LysM, putative peptidoglycan-binding, domain containing 1; Lysmd1; RP11-68I18.5; SB145

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
388695

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96S90

Gene Symbols:
LYSMD1

Immunogen:
Recombinant protein corresponding to Human LYSMD1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG