PIPA555868

SDE2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555868-Each-of-1 In Stock ₹ 47,015.22

PIPA555868 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SDE2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SDE2

Gene Alias

C1orf55; dJ671D7.1; FLJ35382; protein SDE2 homolog; Replication stress response regulator SDE2; RGD1305572; SDE2; SDE2 telomere maintenance homolog; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55; UPF0667 protein C1orf55 homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

163859

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6IQ49

Gene Symbols

SDE2

Immunogen

Recombinant protein corresponding to Human SDE2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAEWVKQQAE REAEKEQKRL ERLQRKLVEP KHCFTSPDYQ QQCHEMAERL EDSVLKGMQA ASSKMVSAEI SENRKRQWPT KSQTDRGASA GKRRCFWLG Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%
  • Involved in both DNA replication and cell cycle control (PubMed:27906959)
  • Unprocessed SDE2 interacts with PCNA via its PIP-box
  • The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis
  • The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain
  • The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner (PubMed:27906959)
  • Binding of SDE2 to PCNA is necessary to counteract damage due to μgtraviolet light induced replication stress
  • The complete degradation of SDE2 is necessary to allow S-phase progression (PubMed:27906959)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA555868

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Antigen:
SDE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SDE2

Gene Alias:
C1orf55; dJ671D7.1; FLJ35382; protein SDE2 homolog; Replication stress response regulator SDE2; RGD1305572; SDE2; SDE2 telomere maintenance homolog; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55; UPF0667 protein C1orf55 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
163859

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6IQ49

Gene Symbols:
SDE2

Immunogen:
Recombinant protein corresponding to Human SDE2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA555869

--


Antigen:
EXOSC10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXOSC10

Gene Alias:
Autoantigen PM/Scl 2; Autoantigen PM/Scl 2 homolog; autoantigen PM-SCL; Exosc10; Exosome component 10; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; p2; p3; p4; PM/Scl-100; PMSCL; PM-Scl; PMSCL2; Polymyositis/scleroderma autoantigen 100 kDa; polymyositis/scleroderma autoantigen 2; Polymyositis/scleroderma autoantigen 2 homolog; RRP6; Rrp6p

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5394

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.10 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q01780

Gene Symbols:
EXOSC10

Immunogen:
Recombinant protein corresponding to Human PM-Scl

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555872

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Antigen:
DIRAS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIRAS3

Gene Alias:
ARHI; DIRAS family GTP binding RAS like 3; DIRAS family GTPase 3; DIRAS family, GTP-binding RAS-like 3; DIRAS3; Distinct subgroup of the Ras family member 3; GTP-binding protein Di-Ras3; NOEY2; ras homolog gene family, member I; RGD1565168; RHOI; rho-related GTP-binding protein RhoI

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9077

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O95661

Gene Symbols:
DIRAS3

Immunogen:
Recombinant protein corresponding to Human DIRAS3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555874

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Antigen:
FLAD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FLAD1

Gene Alias:
A930017E24Rik; fa92c06; FAD pyrophosphorylase; FAD synthase; FAD synthase region; FAD synthetase; FAD1; FAD1 flavin adenine dinucleotide synthetase homolog; Fad1, flavin adenine dinucleotide synthetase, homolog; FADS; FAD-synthetase; FLAD1; Flavin adenine dinucleotide synthase; flavin adenine dinucleotide synthetase; flavin adenine dinucleotide synthetase 1; FMN adenylyltransferase; hypothetical protein LOC506682; LSMFLAD; Molybdenum cofactor biosynthesis protein-like region; PP591; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast); RP11-307C12.7; wu:fa92c06; zgc:91843

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80308

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8NFF5

Gene Symbols:
FLAD1

Immunogen:
Recombinant protein corresponding to Human FLAD1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG