PIPA555937
HCAR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA555937-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA555937 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
HCAR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HCAR2
Gene Alias
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
338442
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8TDS4
Gene Symbols
HCAR2
Immunogen
Recombinant protein corresponding to Human HCAR2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: NRCLQRKMTG EPDNNRSTSV ELTGDPNKTR GAPEALMANS GEPWSPSYLG P Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 67%
- GPR109A (also known as HCA2, HM74a, and NIACR1) is a 42kDa G-protein coupled receptor that belongs to a family of three hydroxyl-carboxylic acid receptors, which also include GPR109B and GPR81
- GPR109A has two known ligands: niacin and butyrate (or its derivative 3-hydroxybutyrate)
- The endogenous ligands for GPR109B and GPR81 are 3-hydroxyl-octanoic acid and 2-hydroxy-propanoate (lactate), respectively
- GPR109A is expressed on adipocytes, neutrophils, Langerhans cells, keratinocytes, intestinal epithelial cells, and intestinal colonic macrophages
- Niacin, also known as nicotinic acid or vitamin B3, is known to improve cholesterol metabolism (LDL/HDL ratio) and reduce inflammation
- It has been demonstrated that this effect is mediated through GPR109A
- Notably, GPR109A also has an essential role in suppressing inflammation and cancer in the colon
- Both GPR109A ligands are produced by colonic commensal bacteria
- In mice, GPR109A expression on intestinal epithelial cells and DCs/macrophages contributes to the suppression of colitis and colon cancer
- In humans, GPR109A is silenced in colon carcinoma cells by DNA methylation, which increases inflammation in the intestinal tract.
Compare Similar Items
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Antigen: HCAR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HCAR2
Gene Alias: G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 338442
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8TDS4
Gene Symbols: HCAR2
Immunogen: Recombinant protein corresponding to Human HCAR2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HCAR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HCAR2
Gene Alias:
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
338442
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8TDS4
Gene Symbols:
HCAR2
Immunogen:
Recombinant protein corresponding to Human HCAR2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: UROD
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Urod
Gene Alias: AI323803; PCT; porphyrinogen carboxylase; porphyrinogen carboxy-lyase; UPD; URO D; UROD; Uro-d; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22275, 29421, 7389
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P06132, P32362, P70697
Gene Symbols: Urod
Immunogen: Recombinant protein corresponding to Human UROD
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
UROD
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Urod
Gene Alias:
AI323803; PCT; porphyrinogen carboxylase; porphyrinogen carboxy-lyase; UPD; URO D; UROD; Uro-d; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22275, 29421, 7389
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P06132, P32362, P70697
Gene Symbols:
Urod
Immunogen:
Recombinant protein corresponding to Human UROD
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CHD1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHD1L
Gene Alias: 4432404A22Rik; ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1 like; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1-like; Snf2p; Unknown (protein for MGC:128792)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9557
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.44 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86WJ1
Gene Symbols: CHD1L
Immunogen: Recombinant protein corresponding to Human CHD1L
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CHD1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHD1L
Gene Alias:
4432404A22Rik; ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1 like; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1-like; Snf2p; Unknown (protein for MGC:128792)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9557
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.44 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86WJ1
Gene Symbols:
CHD1L
Immunogen:
Recombinant protein corresponding to Human CHD1L
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ESPN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Espn
Gene Alias: actin cytoskeletal regulatory protein; autosomal recessive deafness type 36 protein; DFNB36; Ectoplasmic specialization protein; espin; Espn; je; jerker; Jerker, deafness locus; LP2654
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 83715
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: B1AK53
Gene Symbols: Espn
Immunogen: Recombinant protein corresponding to Human ESPN
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ESPN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Espn
Gene Alias:
actin cytoskeletal regulatory protein; autosomal recessive deafness type 36 protein; DFNB36; Ectoplasmic specialization protein; espin; Espn; je; jerker; Jerker, deafness locus; LP2654
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
83715
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
B1AK53
Gene Symbols:
Espn
Immunogen:
Recombinant protein corresponding to Human ESPN
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG