PIPA556375

FRS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA556375-Each-of-1 In Stock ₹ 47,015.22

PIPA556375 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

FRS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FRS3

Gene Alias

4930417B13Rik; AI449674; FGFR substrate 3; FGFR-signaling adaptor SNT2; Fibroblast growth factor receptor substrate 3; FRS2B; Frs2beta; FRS2-beta; FRS3; Snt2; SNT-2; Suc1-associated neurotrophic factor target 2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); testicular tissue protein Li 71

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10817

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O43559

Gene Symbols

FRS3

Immunogen

Recombinant protein corresponding to Human FRS3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: EEPVIITRNS HPAELDLPRA PQPPNALGYT VSSFSNGCPG EGPRFSAPRR LSTSSLRHPS LGEESTHALI APDEQSHTYV NTPASEDDHR Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%
  • FRS3 (fibroblast growth factor receptor substrate 3), also known as FRS2B (FRS2-beta), is a 492 amino acid lipid-anchor adapter protein that contains one IRS-type PTB domain
  • Colocalizing to neural tissues with Tuj1, FRS3 functions as a feedback inhibitor of EGFR family members by preventing heterodimer formation between EGFR and ErbB2, thereby acting as a potential tumor suppressor
  • FRS3 is phosphorylated upon stimulation by FGF-2 or NGF and, acting as an adapter protein, links c-Fgr and NGF receptors to downstream signaling pathways
  • Interfering with the phosphorylation and nuclear translocation of ERK-2, FRS3 down-regulates ERK-2 expression
  • FRS3 likely interacts directly with GRB2, SH-PTP2, Flg, and Trk A, and may be involved in MAP kinase activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA556375

--


Antigen:
FRS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FRS3

Gene Alias:
4930417B13Rik; AI449674; FGFR substrate 3; FGFR-signaling adaptor SNT2; Fibroblast growth factor receptor substrate 3; FRS2B; Frs2beta; FRS2-beta; FRS3; Snt2; SNT-2; Suc1-associated neurotrophic factor target 2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); testicular tissue protein Li 71

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O43559

Gene Symbols:
FRS3

Immunogen:
Recombinant protein corresponding to Human FRS3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556376

--


Antigen:
TJAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TJAP1

Gene Alias:
0610041D19Rik; AI415281; AW121008; hdlg-binding protein Pilt; Pilt; Protein incorporated later into tight junctions; sb:eu465; si:dkey-109m21.1; tight junction associated protein 1; tight junction associated protein 1 (peripheral); tight junction associated protein 1 (peripheral) isoform 1; tight junction associated protein 1 (peripheral) isoform 2; Tight junction protein 4; tight junction protein 4 (peripheral); tight junction-associated protein 1; TJAP1; TJP4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
316233, 74094, 93643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5JTD0, Q9DCD5

Gene Symbols:
TJAP1

Immunogen:
Recombinant protein corresponding to Human TJAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556377

--


Antigen:
TJAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TJAP1

Gene Alias:
0610041D19Rik; AI415281; AW121008; hdlg-binding protein Pilt; Pilt; Protein incorporated later into tight junctions; sb:eu465; si:dkey-109m21.1; tight junction associated protein 1; tight junction associated protein 1 (peripheral); tight junction associated protein 1 (peripheral) isoform 1; tight junction associated protein 1 (peripheral) isoform 2; Tight junction protein 4; tight junction protein 4 (peripheral); tight junction-associated protein 1; TJAP1; TJP4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
93643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5JTD0

Gene Symbols:
TJAP1

Immunogen:
Recombinant protein corresponding to Human TJAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556380

--


Antigen:
KLC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KLC4

Gene Alias:
1200014P03Rik; AA408085; AW146303; bA387M24.3; Kinesin light chain 4; kinesin-like 8; kinesin-like protein 8; KLC 4; KLC4; KNSL8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89953

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NSK0

Gene Symbols:
KLC4

Immunogen:
Recombinant protein corresponding to Human KLC4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG