PIPA556888

NALCN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA556888-Each-of-1 In Stock ₹ 47,015.22

PIPA556888 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

NALCN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NALCN

Gene Alias

A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

259232

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8IZF0

Gene Symbols

NALCN

Immunogen

Recombinant protein corresponding to Human NALCN

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA556053

--

Img

Thermo Scientific

PIPA556927

--

Img

Thermo Scientific

PIPA556652

--

Img

Thermo Scientific

PIPA555299

--

Img

Thermo Scientific

PIPA556485

--

Img

Thermo Scientific

PIPA555725

--

Img

Thermo Scientific

PIPA555649

--

Img

Thermo Scientific

PIPA556889

--

Description

  • Immunogen sequence: QDNSMQPETS SQQQLLSPTL SDRGGSRQDA ADAGKPQRKF GQWRLPSAPK PISHSVSSVN LRFGGRTTMK SVVCKMNPMT DAASCGSEVK KWWT Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%
  • Nalcn is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions
  • Nalcn regulates the resting membrane potential and controls neuronal excitability (PubMed:17448995)
  • Neuropeptides such as neurotensin and substance P (SP) stimulate the firing of action potentials by activating NALCN through a SRC family kinases-dependent pathway
  • In addition to its baseline activity, Nalcn activity is enhanced/modulated by several GPCRs, is required for normal respiratory rhythm and neonatal survival, is involved in systemic osmoregulation by controlling the serum sodium concentration
  • Nalcn is partly responsible for the substance P-induced depolarization and regulation of the intestinal pace-making activity in the interstitial cells of Cajal
  • Further, Nalcn plays a critical role in both maintenance of spontaneous firing of substantia nigra pars reticulata (SNr) neurons and physiological modulation of SNr neuron excitability
  • Diseases associated with NALCN include Congenital contractures of the limbs and face, Hypotonia, Developmental Delay and Hypotonia, Infantile Psychomotor Retardation And Characteristic Facies 1.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA556888

--


Antigen:
NALCN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NALCN

Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
259232

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IZF0

Gene Symbols:
NALCN

Immunogen:
Recombinant protein corresponding to Human NALCN

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556889

--


Antigen:
CACNA2D4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cacna2d4

Gene Alias:
5730412N02Rik; BE686333; Cacna2d4; calcium channel, voltage-dependent, alpha 2/delta subunit 4; calcium voltage-gated channel auxiliary subunit alpha2delta 4; LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-4; RCD4; RGD1562038; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4; voltage-gated calcium channel alpha(2)delta-4 subunit; voltage-gated calcium channel subunit alpha-2/delta-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
93589

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q7Z3S7

Gene Symbols:
Cacna2d4

Immunogen:
Recombinant protein corresponding to Human CACNA2D4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556891

--


Antigen:
COA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COA3

Gene Alias:
1810033A19Rik; Ccdc56; COA3; coiled-coil domain containing 56; coiled-coil domain-containing protein 56; cytochrome c oxidase assembly factor 3; cytochrome c oxidase assembly factor 3 homolog, mitochondrial; cytochrome c oxidase assembly protein 3 homolog, mitochondrial; D11Ertd99e; HSPC009; mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa; MITRAC12; RGD1564337

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9Y2R0

Gene Symbols:
COA3

Immunogen:
Recombinant protein corresponding to Human COA3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA556892

--


Antigen:
TSPYL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPYL1

Gene Alias:
testis-specific protein, Y-encoded-like 1; testis-specific Y-encoded-like protein 1; TSPY like 1; Tspyl; Tspyl1; TSPY-like 1; TSPY-like protein 1; Y encoded

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H0U9

Gene Symbols:
TSPYL1

Immunogen:
Recombinant protein corresponding to Human TSPYL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG