PIPA556998
COMMD1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA556998-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA556998 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
COMMD1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
COMMD1
Gene Alias
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
150684
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8N668
Gene Symbols
COMMD1
Immunogen
Recombinant protein corresponding to Human COMMD1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AQDTFHGYPG ITEELLRSQL YPEVPPEEFR PFLAKMRGIL KSIASADMDF NQLEAFLTAQ TKKQGGITSD QAAV Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 92%
- Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins
- Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activiy and dissocoiates CAND1 from CUL1 and CUL2
- Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation
- Down-regulates NF-kappa-B activity
- Involved in the regulation of membrane expression and ubiquitination of SLC12A2
- Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L
- Promotes the localization of SCNN1D to recycling endosomes
- Promotes CFTR cell surface expression through regulation of its ubiquitination
- Down-regulates SOD1 activity by interfering with its homodimerization
- Plays a role in copper ion homeostasis
- Involved in copper-dependent ATP7A trafficking between the trans- Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes
- Can bind one copper ion per monomer
- May function to facilitate biliary copper excretion within hepatocytes
- Binds to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2)
- Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.
Compare Similar Items
Show Difference
Antigen: COMMD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COMMD1
Gene Alias: AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 150684
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N668
Gene Symbols: COMMD1
Immunogen: Recombinant protein corresponding to Human COMMD1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
COMMD1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COMMD1
Gene Alias:
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
150684
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N668
Gene Symbols:
COMMD1
Immunogen:
Recombinant protein corresponding to Human COMMD1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RIN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RIN2
Gene Alias: 2010003K16Rik; 4632403N06Rik; AW821980; MACS; RAB5 interacting protein 2; ras and Rab interactor 2; RAS association (RalGDS/AF-6) domain containing protein JC265; RAS association domain family 4; Ras inhibitor JC265; ras interaction/interference protein 2; RASSF4; Rin2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54453
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8WYP3
Gene Symbols: RIN2
Immunogen: Recombinant protein corresponding to Human RIN2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RIN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RIN2
Gene Alias:
2010003K16Rik; 4632403N06Rik; AW821980; MACS; RAB5 interacting protein 2; ras and Rab interactor 2; RAS association (RalGDS/AF-6) domain containing protein JC265; RAS association domain family 4; Ras inhibitor JC265; ras interaction/interference protein 2; RASSF4; Rin2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54453
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8WYP3
Gene Symbols:
RIN2
Immunogen:
Recombinant protein corresponding to Human RIN2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: APLF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APLF
Gene Alias: 2010301N04Rik; AI452191; APFL; APLF; aprataxin- and PNK-like factor; Aprataxin and PNK-like factor; aprataxin and PNKP like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; RGD1565557; XIP1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 200558
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IW19
Gene Symbols: APLF
Immunogen: Recombinant protein corresponding to Human APLF
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APLF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APLF
Gene Alias:
2010301N04Rik; AI452191; APFL; APLF; aprataxin- and PNK-like factor; Aprataxin and PNK-like factor; aprataxin and PNKP like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; RGD1565557; XIP1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
200558
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IW19
Gene Symbols:
APLF
Immunogen:
Recombinant protein corresponding to Human APLF
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: APLF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APLF
Gene Alias: 2010301N04Rik; AI452191; APFL; APLF; aprataxin- and PNK-like factor; Aprataxin and PNK-like factor; aprataxin and PNKP like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; RGD1565557; XIP1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 200558
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IW19
Gene Symbols: APLF
Immunogen: Recombinant protein corresponding to Human APLF
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APLF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APLF
Gene Alias:
2010301N04Rik; AI452191; APFL; APLF; aprataxin- and PNK-like factor; Aprataxin and PNK-like factor; aprataxin and PNKP like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; RGD1565557; XIP1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
200558
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IW19
Gene Symbols:
APLF
Immunogen:
Recombinant protein corresponding to Human APLF
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG