PIPA557051

DGUOK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA557051-Each-of-1 In Stock ₹ 47,528.58

PIPA557051 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

DGUOK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DGUOK

Gene Alias

deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; dGK1; dGK2; dGK3; DGUOK; MTDPS3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1716

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q16854

Gene Symbols

DGUOK

Immunogen

Recombinant protein corresponding to Human DGUOK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: STFVKLLTKT YPEWHVATEP VATWQNIQAA GTQKACTAQS LGNLLDMMYR EPARWSYTFQ TFSFLSRLKV QLEPFPEKLL QARKPVQI Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 77%
  • Mitochondrial deoxyguanosine kinase (DGUOK) is required for the phosphorylation of several deoxyribonucleosides and certain purine deoxykribonucleoside analogs widely employed as antiviral and chemotherapeutic agents
  • Purine deoxyribonucleoside analogs are extensively used in treatment of lymphoproliferative disorders
  • These compounds are administered as pro-drugs, and their efficiency is dependent on intracellular phosphorylation to the corresponding triphosphates
  • In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by 2 deoxyribonucleoside kinases: cytosolic deoxycytidine kinase (DCK) and mitochondrial deoxyguanosine kinase (DGUOK also known as DGK)
  • DGUOK expression is ubiquitous, with highest levels in muscle, brain, liver and lymphoid tissues
  • Defects in DGUOK are a cause of mitochondrial DNA depletion syndrome (MDS)
  • MDS is a clinically heterogeneous group of disorders characterized by a reduction in mitochondrial DNA (mtDNA) copy number
  • Primary mtDNA depletion is inherited as an autosomal recessive trait and may affect single organs, typically muscle or liver, or multiple tissues.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA557051

--


Antigen:
DGUOK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DGUOK

Gene Alias:
deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; dGK1; dGK2; dGK3; DGUOK; MTDPS3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1716

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q16854

Gene Symbols:
DGUOK

Immunogen:
Recombinant protein corresponding to Human DGUOK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA557052

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Antigen:
ARMH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1orf228

Gene Alias:
Armadillo-like helical domain containing protein 1; ARMH1; C1orf228; chromosome 1 open reading frame 228; NCRNA00082; p40; uncharacterized protein C1orf228

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
339541

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6PIY5

Gene Symbols:
C1orf228

Immunogen:
Recombinant protein corresponding to Human C1orf228

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA557057

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Antigen:
JIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8IP2

Gene Alias:
3230402N03Rik; AI847694; AW049958; C-Jun-amino-terminal kinase-interacting protein 2; homologous to mouse JIP-1; IB 2; Ib2; IB-2; Islet brain 2; islet-brain 2; islet-brain-2; JIP 2; JIP2; JIP-2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; Mapk8ip2; mitogen activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8-interacting protein 2; PRKM8IPL; R75148; si:dkey-180h12.2; si:dkey-181m21.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23542

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
Lot-Specific

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q13387

Gene Symbols:
MAPK8IP2

Immunogen:
Recombinant protein corresponding to Human JIP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA557058

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Antigen:
ZNF793

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF793

Gene Alias:
Zinc finger protein 793; ZNF793

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
390927

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6ZN11

Gene Symbols:
ZNF793

Immunogen:
Recombinant protein corresponding to Human ZNF793

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG