PIPA557444

LYAR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA557444-Each-of-1 In Stock ₹ 50,309.28

PIPA557444 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

LYAR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LYAR

Gene Alias

apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55646

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NX58

Gene Symbols

LYAR

Immunogen

Recombinant protein corresponding to Human LYAR

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RELLEQISAF DNVPRKKAKF QNWMKNSLKV HNESILDQVW NIFSEASNSE PVNKEQDQRP LHPVANPHAE ISTKVPASKV KDAVEQQGEV KKNKRERKEE R Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 67%
  • Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227)
  • Also acts at the level of transcription regulation
  • Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918)
  • In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580)
  • Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918)
  • Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (PubMed:31413131)
  • In addition, inhibits NF-kappa-B-mediated expression of proinflammatory cytokines (PubMed:31413131)
  • Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells
  • Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA557444

--


Antigen:
LYAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYAR

Gene Alias:
apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55646

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NX58

Gene Symbols:
LYAR

Immunogen:
Recombinant protein corresponding to Human LYAR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557445

--


Antigen:
SEC31B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEC31B

Gene Alias:
Protein transport protein Sec31B; sc31b; SEC31 homolog B; SEC31 homolog B, COPII coat complex component; SEC31 homolog B, COPII coating complex component; SEC31B; SEC31B-1; SEC31L2; SEC31-like 2; SEC31-like protein 2; SEC31-related protein B; secretory pathway component Sec31B-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NQW1

Gene Symbols:
SEC31B

Immunogen:
Recombinant protein corresponding to Human SEC31B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557448

--


Antigen:
C1orf177

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LEXM

Gene Alias:
BC055111; C1orf177; cDNA sequence BC055111; LEM; LEXM; Lymphocyte expansion molecule; RGD1559493; similar to Hypothetical protein MGC58608; uncharacterized protein C1orf177; uncharacterized protein C1orf177 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
163747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q3ZCV2

Gene Symbols:
LEXM

Immunogen:
Recombinant protein corresponding to Human C1orf177

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557449

--


Antigen:
UBTD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBTD2

Gene Alias:
4930571L24; 9630054F20Rik; AI645720; DCUBP; DC-UbP; Dendritic cell-derived ubiquitin-like protein; RGD1305506; SB72; ubiquitin domain containing 2; ubiquitin domain-containing protein 2; Ubiquitin-like protein SB72; Ubtd2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
92181

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WUN7

Gene Symbols:
UBTD2

Immunogen:
Recombinant protein corresponding to Human UBTD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG