PIPA557737

CXXC4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA557737-Each-of-1 In Stock ₹ 47,015.22

PIPA557737 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

CXXC4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CXXC4

Gene Alias

9330210J02Rik; C030003J12Rik; CXXC finger 4; CXXC finger protein 4; CXXC4; CXXC-type zinc finger protein 4; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex); Idax; inhibition of the Dvl and axin complex protein; inhibitor of the Dvl and Axin complex

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80319

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9H2H0

Gene Symbols

CXXC4

Immunogen

Recombinant protein corresponding to Human CXXC4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA555099

--

Img

Thermo Scientific

PIPA556979

--

Img

Thermo Scientific

PIPA554774

--

Img

Thermo Scientific

PIPA557612

--

Img

Thermo Scientific

PIPA557613

--

Img

Thermo Scientific

PIPA557227

--

Img

Thermo Scientific

PIPA554850

--

Img

Thermo Scientific

PIPA557062

--

Description

  • Immunogen sequence: GSRTSMHHRN DSQRLGKAGC PPEPSLQMAN TNFLSTLSPE HCRPLAGECM NKLKCGAAEA E Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%
  • CXXC4 is zinc finger protein that binds directly to the PDZ domain of DVL1, a protein involved in the Wnt signaling pathway, through its C-terminal region
  • CXXC4 interaction with DVL1 competes with DVL1-AXIN binding, although the affinity of DVL1 for CXXC4 is lower than that for AXIN
  • In mouse fibroblasts, CXXC4 suppressed Wnt3a induction of beta-catenin and inhibited Wnt3a-dependent TCF4 activation, suggesting that CXXC4 acts as a negative regulator of the Wnt signaling pathway and functions between DVL and beta-catenin
  • Recent reports suggest that decreased CXXC4 expression is associated with kidney cancer metastasis, cell proliferation, reduced apoptosis in response to cancer drugs, and upregulation of genes involved with proliferation, invasion and cell survival, suggesting that CXXC4 plays a critical role in tumor progression in kidney cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA557737

--


Antigen:
CXXC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXXC4

Gene Alias:
9330210J02Rik; C030003J12Rik; CXXC finger 4; CXXC finger protein 4; CXXC4; CXXC-type zinc finger protein 4; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex); Idax; inhibition of the Dvl and axin complex protein; inhibitor of the Dvl and Axin complex

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80319

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9H2H0

Gene Symbols:
CXXC4

Immunogen:
Recombinant protein corresponding to Human CXXC4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557738

--


Antigen:
DPCD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPCD

Gene Alias:
5330431N19Rik; deleted in a mouse model of primary ciliary dyskinesia; deleted in primary ciliary dyskinesia; deleted in primary ciliary dyskinesia homolog (mouse); DPCD; Ndac; neighbor of Dac; protein DPCD; RGD1307648; RP11-529I10.4; RP11-529I104

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25911

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BVM2

Gene Symbols:
DPCD

Immunogen:
Recombinant protein corresponding to Human DPCD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557739

--


Antigen:
DPCD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPCD

Gene Alias:
5330431N19Rik; deleted in a mouse model of primary ciliary dyskinesia; deleted in primary ciliary dyskinesia; deleted in primary ciliary dyskinesia homolog (mouse); DPCD; Ndac; neighbor of Dac; protein DPCD; RGD1307648; RP11-529I10.4; RP11-529I104

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25911

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BVM2

Gene Symbols:
DPCD

Immunogen:
Recombinant protein corresponding to Human DPCD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557740

--


Antigen:
PPP2R5B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP2R5B

Gene Alias:
B56B; B'beta; BC026670; FLJ35411; LOC100909468; PP2A; PP2A B subunit isoform B56-beta; PP2A B subunit isoform B'-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; Ppp2r5b; PR61B; protein phosphatase 2 regulatory subunit B', beta; protein phosphatase 2 regulatory subunit B'beta; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B', beta; protein phosphatase 2, regulatory subunit B', beta isoform; protein phosphotase 2, regulatory subunit B (B56), beta isoform; rCG_47223; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225849, 309179, 5526

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q15173, Q6PD28, Q80W83

Gene Symbols:
PPP2R5B

Immunogen:
Recombinant protein corresponding to Human PPP2R5B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG