PIPA557840
TRIP12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA557840-Each-of-1 | In Stock | ₹ 50,651.52 |
PIPA557840 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,651.52
GST (18%): ₹ 9,117.274
Total Price: ₹ 59,768.794
Antigen
TRIP12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRIP12
Gene Alias
1110036I07Rik; 6720416K24Rik; AA410158; E3 ubiquitin-protein ligase for Arf; E3 ubiquitin-protein ligase TRIP12; gene trap locus 6; Gtl6; HECT-type E3 ubiquitin transferase TRIP12; KIAA0045; probable E3 ubiquitin-protein ligase TRIP12; thyroid hormone receptor interactor 12; thyroid receptor interacting protein 12; thyroid receptor interactor TRIP12; thyroid receptor-interacting protein 12; TR-interacting protein 12; TRIP12; TRIP-12; ULF
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9320
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q14669
Gene Symbols
TRIP12
Immunogen
Recombinant protein corresponding to Human TRIP12
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AMCKEIIPTS EFINSKLTAK ANRQLQDPLV IMTGNIPTWL TELGKTCPFF FPFDTRQMLF YVTAFDRDRA MQRLLDTNPE INQSDSQD Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%
- E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair
- Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardeless of the presence of lysine residues in target proteins
- In normal cells, mediates ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A, a lysine-less tumor suppressor required for p53/TP53 activation under oncogenic stress
- In cancer cells, however, isoform p19ARF/ARF and TRIP12 are located in different cell compartments, preventing isoform p19ARF/ARF ubiquitination and degradation
- Does not mediate ubiquitination of isoform p16-INK4a of CDKN2A
- Also catalyzes ubiquitination of NAE1 and SMARCE1, leading to their degradation
- Ubiquitination and degradation of target proteins is regulated by interaction with proteins such as MYC, TRADD or SMARCC1, which disrupt the interaction between TRIP12 and target proteins
- Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.
Compare Similar Items
Show Difference
Antigen: TRIP12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRIP12
Gene Alias: 1110036I07Rik; 6720416K24Rik; AA410158; E3 ubiquitin-protein ligase for Arf; E3 ubiquitin-protein ligase TRIP12; gene trap locus 6; Gtl6; HECT-type E3 ubiquitin transferase TRIP12; KIAA0045; probable E3 ubiquitin-protein ligase TRIP12; thyroid hormone receptor interactor 12; thyroid receptor interacting protein 12; thyroid receptor interactor TRIP12; thyroid receptor-interacting protein 12; TR-interacting protein 12; TRIP12; TRIP-12; ULF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9320
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q14669
Gene Symbols: TRIP12
Immunogen: Recombinant protein corresponding to Human TRIP12
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TRIP12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRIP12
Gene Alias:
1110036I07Rik; 6720416K24Rik; AA410158; E3 ubiquitin-protein ligase for Arf; E3 ubiquitin-protein ligase TRIP12; gene trap locus 6; Gtl6; HECT-type E3 ubiquitin transferase TRIP12; KIAA0045; probable E3 ubiquitin-protein ligase TRIP12; thyroid hormone receptor interactor 12; thyroid receptor interacting protein 12; thyroid receptor interactor TRIP12; thyroid receptor-interacting protein 12; TR-interacting protein 12; TRIP12; TRIP-12; ULF
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9320
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q14669
Gene Symbols:
TRIP12
Immunogen:
Recombinant protein corresponding to Human TRIP12
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: STK11IP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK11IP
Gene Alias: 1200014D22Rik; BB131189; KIAA1898; LIP1; LKB1-interacting protein 1; LKB1IP; serine/threonine kinase 11 interacting protein; serine/threonine kinase 11-interacting protein; serine/threonine-protein kinase 11-interacting protein; STK11 interacting protein; STK11IP; STK11IP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114790
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N1F8
Gene Symbols: STK11IP
Immunogen: Recombinant protein corresponding to Human STK11IP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
STK11IP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK11IP
Gene Alias:
1200014D22Rik; BB131189; KIAA1898; LIP1; LKB1-interacting protein 1; LKB1IP; serine/threonine kinase 11 interacting protein; serine/threonine kinase 11-interacting protein; serine/threonine-protein kinase 11-interacting protein; STK11 interacting protein; STK11IP; STK11IP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114790
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N1F8
Gene Symbols:
STK11IP
Immunogen:
Recombinant protein corresponding to Human STK11IP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: STK11IP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK11IP
Gene Alias: 1200014D22Rik; BB131189; KIAA1898; LIP1; LKB1-interacting protein 1; LKB1IP; serine/threonine kinase 11 interacting protein; serine/threonine kinase 11-interacting protein; serine/threonine-protein kinase 11-interacting protein; STK11 interacting protein; STK11IP; STK11IP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114790
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N1F8
Gene Symbols: STK11IP
Immunogen: Recombinant protein corresponding to Human STK11IP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
STK11IP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK11IP
Gene Alias:
1200014D22Rik; BB131189; KIAA1898; LIP1; LKB1-interacting protein 1; LKB1IP; serine/threonine kinase 11 interacting protein; serine/threonine kinase 11-interacting protein; serine/threonine-protein kinase 11-interacting protein; STK11 interacting protein; STK11IP; STK11IP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114790
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N1F8
Gene Symbols:
STK11IP
Immunogen:
Recombinant protein corresponding to Human STK11IP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: WDSUB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WDSUB1
Gene Alias: 1700048E19Rik; 2610014F08Rik; UBOX6; WD repeat and SAM domain containing 1; WD repeat, SAM and U-box domain containing 1; WD repeat, SAM and U-box domain-containing protein 1; WD repeat, sterile alpha motif and U-box domain containing 1; WDSAM1; Wdsub1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 151525
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N9V3
Gene Symbols: WDSUB1
Immunogen: Recombinant protein corresponding to Human WDSUB1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
WDSUB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WDSUB1
Gene Alias:
1700048E19Rik; 2610014F08Rik; UBOX6; WD repeat and SAM domain containing 1; WD repeat, SAM and U-box domain containing 1; WD repeat, SAM and U-box domain-containing protein 1; WD repeat, sterile alpha motif and U-box domain containing 1; WDSAM1; Wdsub1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
151525
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N9V3
Gene Symbols:
WDSUB1
Immunogen:
Recombinant protein corresponding to Human WDSUB1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG