PIPA557875

OPA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA557875-Each-of-1 In Stock ₹ 49,710.36

PIPA557875 - Each of 1

₹ 49,710.36

In Stock

Quantity

1

Base Price: ₹ 49,710.36

GST (18%): ₹ 8,947.865

Total Price: ₹ 58,658.225

Antigen

OPA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OPA1

Gene Alias

1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4976

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O60313

Gene Symbols

OPA1

Immunogen

Recombinant protein corresponding to Human OPA1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KEGCTVSPET ISLNVKGPGL QRMVLVDLPG VINTVTSGMA PDTKETIFSI SKAYMQNPNA IILCIQDGSV DAERSIVTDL VSQMDPHG Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%
  • OPA1 is a dynamin-related GTPase that is critical for the maintenance of mitochondrial morphology and mtDNA
  • The most commonly associated phenotype with OPA1 mutations is heterozygous optic atrophy, a heterozygous dominant trait that causes reduced visual clarity and sometimes blindness
  • The disease usually begins in childhood and increases in severity throughout the life of affected individuals
  • Usually, this phenotype is attributed to the degeneration of optic nerve fibers
  • Interestingly, the same type of nerve degeneration seems to be partially causative of certain schizophrenia characteristics
  • OPA1 dysfunction also seems to be implicated in this case; mitochondrial networks associated with critical nerves seem to link schizophrenia and OPA1
  • The dysfunction is associated with issues with apoptosis and normal cellular metabolic regulation, all regulated through OPA1.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA557875

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Antigen:
OPA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OPA1

Gene Alias:
1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4976

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O60313

Gene Symbols:
OPA1

Immunogen:
Recombinant protein corresponding to Human OPA1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557877

--


Antigen:
TBC1D14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TBC1D14

Gene Alias:
2810413P16Rik; AU043625; C86258; D5Ertd110e; Kiaa1322; mKIAA1322; TBC1 domain family member 14; TBC1 domain family, member 14; Tbc1d14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57533

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9P2M4

Gene Symbols:
TBC1D14

Immunogen:
Recombinant protein corresponding to Human TBC1D14

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA557880

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Antigen:
PCCB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCCB

Gene Alias:
1300012P06Rik; AI314687; PCCase subunit beta; Pccb; Propanoyl-CoA:carbon dioxide ligase subunit beta; propionyl CoA carboxylase, beta polypeptide; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-coA carboxylase B; Propionyl-CoA carboxylase beta chain precursor; propionyl-CoA carboxylase beta chain, mitochondrial; propionyl-CoA carboxylase beta subunit; propionyl-CoA carboxylase subunit beta; R74805

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5096

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P05166

Gene Symbols:
PCCB

Immunogen:
Recombinant protein corresponding to Human PCCB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557881

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Antigen:
BITE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEP70

Gene Alias:
6720484E09Rik; BITE; C030018L16Rik; centrosomal protein 70; centrosomal protein 70kDa; Centrosomal protein of 70 kDa; CEP70; I79_009119; p10-binding protein; testicular tissue protein Li 36

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8NHQ1

Gene Symbols:
CEP70

Immunogen:
Recombinant protein corresponding to Human BITE

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG