PIPA557996

DOCK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA557996-Each-of-1 In Stock ₹ 47,015.22

PIPA557996 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

DOCK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dock3

Gene Alias

dedicator of cytokinesis 3; dedicator of cyto-kinesis 3; dedicator of cytokinesis protein 3; DOCK3; dok-3; KIAA0299; mKIAA0299; MOCA; Modifier of cell adhesion; PBP; Presenilin-binding protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1795

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8IZD9

Gene Symbols

Dock3

Immunogen

Recombinant protein corresponding to Human DOCK3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: FEVVDSDQIS VSDLYKMHLS SRQSVQQSTS QVDTMRPRHG ETCRMPVPHH FFLSLKSFTY NTIGEDTDVF FSLYDMREGK QISERFLVRL NKNG Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%
  • Dedicator of cytokinesis3 (DOCK3), also named as MOCA and PBP, is a ∽180 kDa protein involved in signaling transduction
  • It is a potential guanine nucleotide exchange factor (GEF) which activate some small GTPases by exchanging bound GDP for free GTP
  • DOCK3 is associated in Alzheimer disease tangles and regulates the accumulation of amyloid precursor protein and beta-amyloid
  • Overexpression of Dock3 in neural cells promotes axonal outgrowth downstream of brain-derived neurotrophic factor (BDNF) signaling
  • DOCK3 binds to and inactivates glycogen synthase kinase-3beta (GSK-3beta) at the plasma membrane, thereby promoting axon branching and microtubule assembly
  • By stimulating actin polymerization and microtubule assembly, DOCK3 plays important roles downstream of BDNF signaling in the CNS.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA557996

--


Antigen:
DOCK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dock3

Gene Alias:
dedicator of cytokinesis 3; dedicator of cyto-kinesis 3; dedicator of cytokinesis protein 3; DOCK3; dok-3; KIAA0299; mKIAA0299; MOCA; Modifier of cell adhesion; PBP; Presenilin-binding protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1795

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IZD9

Gene Symbols:
Dock3

Immunogen:
Recombinant protein corresponding to Human DOCK3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA557997

--


Antigen:
SR140

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
U2SURP

Gene Alias:
140 kDa Ser/Arg-rich domain protein; 2610101N10Rik; AU023006; fSAPa; functional spliceosome-associated protein a; KIAA0332; mp:zf637-1-000918; RGD1307882; Ser/Arg-rich domain protein, 140 kDa; si:dkey-181m9.9; SR140; U2 associated SR140 protein; U2 snRNP associated SURP domain containing; U2 snRNP-associated SURP domain containing; U2 snRNP-associated SURP motif-containing protein; U2-associated protein SR140; u2-associated protein SR140-like protein; U2-associated SR140 protein; U2SURP; wu:fa03e02; wu:fb38b01; wu:fc75d03

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23350, 315903, 67958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15042, Q6NV83

Gene Symbols:
U2SURP

Immunogen:
Recombinant protein corresponding to Human SR140

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA558000

--


Antigen:
RPUSD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPUSD3

Gene Alias:
AI527266; Mitochondrial mRNA pseudouridine synthase RPUSD3; RGD1307582; RNA pseudouridylate synthase domain containing 3; RNA pseudouridylate synthase domain-containing protein 3; Rpusd3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
285367

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6P087

Gene Symbols:
RPUSD3

Immunogen:
Recombinant protein corresponding to Human RPUSD3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA558001

--


Antigen:
RPUSD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPUSD3

Gene Alias:
AI527266; Mitochondrial mRNA pseudouridine synthase RPUSD3; RGD1307582; RNA pseudouridylate synthase domain containing 3; RNA pseudouridylate synthase domain-containing protein 3; Rpusd3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
101122, 285367, 362416

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14AI6, Q6P087

Gene Symbols:
RPUSD3

Immunogen:
Recombinant protein corresponding to Human RPUSD3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG