PIPA558027
FAM175B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558027-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA558027 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
FAM175B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ABRAXAS2
Gene Alias
AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23172
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q15018
Gene Symbols
ABRAXAS2
Immunogen
Recombinant protein corresponding to Human FAM175B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DVEKSERVVE SCQAEVNKLR RQITQRKNEK EQERRLQQAV LSRQMPSESL DPAFSPRMPS SGFAAEGRST LGDA Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 92%
- Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985)
- May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690)
- Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins
- Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665)
- Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097)
- Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985)
- Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148)
- Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: FAM175B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABRAXAS2
Gene Alias: AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23172
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q15018
Gene Symbols: ABRAXAS2
Immunogen: Recombinant protein corresponding to Human FAM175B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM175B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
AA589499; Abraxas brother; abraxas brother 1; abraxas brother protein 1; Abraxas2; Abro1; AI853413; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; C430003P19Rik; Em:AC068896.4; FAM175B; family with sequence similarity 175 member B; family with sequence similarity 175, member B; KIAA0157; Protein FAM175B; RGD1308918
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Recombinant protein corresponding to Human FAM175B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Enkurin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ENKUR
Gene Alias: 4933434I06Rik; AU016229; C10orf63; CFAP106; Enkur; Enkurin; enkurin, TRPC channel interacting protein; RGD1309839
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 219670
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8TC29
Gene Symbols: ENKUR
Immunogen: Recombinant protein corresponding to Human Enkurin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Enkurin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ENKUR
Gene Alias:
4933434I06Rik; AU016229; C10orf63; CFAP106; Enkur; Enkurin; enkurin, TRPC channel interacting protein; RGD1309839
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
219670
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8TC29
Gene Symbols:
ENKUR
Immunogen:
Recombinant protein corresponding to Human Enkurin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Enkurin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ENKUR
Gene Alias: 4933434I06Rik; AU016229; C10orf63; CFAP106; Enkur; Enkurin; enkurin, TRPC channel interacting protein; RGD1309839
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 219670
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8TC29
Gene Symbols: ENKUR
Immunogen: Recombinant protein corresponding to Human Enkurin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Enkurin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ENKUR
Gene Alias:
4933434I06Rik; AU016229; C10orf63; CFAP106; Enkur; Enkurin; enkurin, TRPC channel interacting protein; RGD1309839
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
219670
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8TC29
Gene Symbols:
ENKUR
Immunogen:
Recombinant protein corresponding to Human Enkurin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MPP7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MPP7
Gene Alias: 1110068J02Rik; 2810038M04Rik; 5430426E14Rik; AI415104; Gm955; MAGUK p55 subfamily member 7; membrane palmitoylated protein 7; membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7); MPP7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 143098
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5T2T1
Gene Symbols: MPP7
Immunogen: Recombinant protein corresponding to Human MPP7
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MPP7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MPP7
Gene Alias:
1110068J02Rik; 2810038M04Rik; 5430426E14Rik; AI415104; Gm955; MAGUK p55 subfamily member 7; membrane palmitoylated protein 7; membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7); MPP7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
143098
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5T2T1
Gene Symbols:
MPP7
Immunogen:
Recombinant protein corresponding to Human MPP7
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG