PIPA558134
AFAP1L2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558134-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA558134 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
AFAP1L2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AFAP1L2
Gene Alias
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
84632
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8N4X5
Gene Symbols
AFAP1L2
Immunogen
Recombinant protein corresponding to Human AFAP1L2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SPTLSCLDNA TEALPADSGP GPTPDEPCIK CPENLGEQQL ESLEPEDPSL RITTVKIQTE QQRISFPPSC PDAVVATPPG ASPPVKD Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 49%
- AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites
- It interacts with and is phosphorylated by c-Src tyrosine kinase
- Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions
- Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer
- Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy
- At least four isoforms of AFAP1L2 are known to exist.
Compare Similar Items
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Antigen: AFAP1L2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AFAP1L2
Gene Alias: actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84632
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8N4X5
Gene Symbols: AFAP1L2
Immunogen: Recombinant protein corresponding to Human AFAP1L2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
AFAP1L2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AFAP1L2
Gene Alias:
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84632
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8N4X5
Gene Symbols:
AFAP1L2
Immunogen:
Recombinant protein corresponding to Human AFAP1L2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MYOZ1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYOZ1
Gene Alias: 2310001N11Rik; alpha-actinin binding protein; AV090278; calcineurin-2; calsarcin 2; calsarcin-2; CS-2; FATZ; filamin-, actinin- and telethonin-binding protein; MYOZ; myoz1; myozenin 1; myozenin precursor; myozenin-1; Protein FATZ; RGD1561064; skeletal muscle-specific protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 58529
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NP98
Gene Symbols: MYOZ1
Immunogen: Recombinant protein corresponding to Human MYOZ1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MYOZ1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYOZ1
Gene Alias:
2310001N11Rik; alpha-actinin binding protein; AV090278; calcineurin-2; calsarcin 2; calsarcin-2; CS-2; FATZ; filamin-, actinin- and telethonin-binding protein; MYOZ; myoz1; myozenin 1; myozenin precursor; myozenin-1; Protein FATZ; RGD1561064; skeletal muscle-specific protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
58529
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NP98
Gene Symbols:
MYOZ1
Immunogen:
Recombinant protein corresponding to Human MYOZ1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HORMAD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HORMAD1
Gene Alias: 4921522K05Rik; Cancer/testis antigen 46; CT46; HORM1; HORMA domain containing 1; HORMA domain containing protein; HORMA domain-containing protein 1; HORMAD1; Newborn ovary HORMA protein; Nohma; RGD1564960; testis tissue sperm-binding protein Li 86P
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84072
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86X24
Gene Symbols: HORMAD1
Immunogen: Recombinant protein corresponding to Human HORMAD1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HORMAD1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HORMAD1
Gene Alias:
4921522K05Rik; Cancer/testis antigen 46; CT46; HORM1; HORMA domain containing 1; HORMA domain containing protein; HORMA domain-containing protein 1; HORMAD1; Newborn ovary HORMA protein; Nohma; RGD1564960; testis tissue sperm-binding protein Li 86P
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84072
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86X24
Gene Symbols:
HORMAD1
Immunogen:
Recombinant protein corresponding to Human HORMAD1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TRAF3IP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRAF3IP1
Gene Alias: 3930402D05Rik; AU041749; IFT54; interleukin 13 receptor alpha 1-binding protein-1; interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; microtubule interacting protein that associates with TRAF3; microtubule-interacting protein associated with TRAF3; microtubule-interacting protein that associates with TRAF3; MIPT3; MIP-T3; SLSN9; TNF receptor-associated factor 3 interacting protein 1; TRAF3 interacting protein 1; TRAF3-interacting protein 1; TRAF3IP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26146
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8TDR0
Gene Symbols: TRAF3IP1
Immunogen: Recombinant protein corresponding to Human TRAF3IP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TRAF3IP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRAF3IP1
Gene Alias:
3930402D05Rik; AU041749; IFT54; interleukin 13 receptor alpha 1-binding protein-1; interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; microtubule interacting protein that associates with TRAF3; microtubule-interacting protein associated with TRAF3; microtubule-interacting protein that associates with TRAF3; MIPT3; MIP-T3; SLSN9; TNF receptor-associated factor 3 interacting protein 1; TRAF3 interacting protein 1; TRAF3-interacting protein 1; TRAF3IP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26146
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8TDR0
Gene Symbols:
TRAF3IP1
Immunogen:
Recombinant protein corresponding to Human TRAF3IP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG