PIPA558189

LPHN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558189-Each-of-1 In Stock ₹ 47,528.58

PIPA558189 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

LPHN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Adgrl1

Gene Alias

2900070I05Rik; ADGRL1; Adhesion G protein-coupled receptor L1; AI182398; calcium-independent alpha-latrotoxin receptor 1; Cirl; Cirl1; CIRL-1; CL1; CL1BA; CLIBA; KIAA0821; latrophilin 1; latrophilin-1; LEC2; Lectomedin-2; Lphh2; LPHN1; mKIAA0821

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22859

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O94910

Gene Symbols

Adgrl1

Immunogen

Recombinant protein corresponding to Human LPHN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: GNHLLTNPVL QPRGGTSPYN TLIAESVGFN PSSPPVFNSP GSYREPKHPL GGREACGMDT LP Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%
  • Adgrl1 (Latrophilin-1) is a calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells
  • Adgrl1 is a receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization, and may be implicated in the regulation of exocytosis
  • The Adgrl1 gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR)
  • Latrophilins may function in both cell adhesion and signal transduction
  • In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane
  • Adgrl1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane
  • Alternative splicing results in multiple variants encoding distinct isoforms of Adgrl1
  • Diseases associated with ADGRL1 include Dermatophytosis and Retinal Degeneration, Late-Onset, Autosomal Dominant.

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Show Difference

Img

Thermo Scientific

PIPA558189

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Antigen:
LPHN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adgrl1

Gene Alias:
2900070I05Rik; ADGRL1; Adhesion G protein-coupled receptor L1; AI182398; calcium-independent alpha-latrotoxin receptor 1; Cirl; Cirl1; CIRL-1; CL1; CL1BA; CLIBA; KIAA0821; latrophilin 1; latrophilin-1; LEC2; Lectomedin-2; Lphh2; LPHN1; mKIAA0821

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22859

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O94910

Gene Symbols:
Adgrl1

Immunogen:
Recombinant protein corresponding to Human LPHN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA558190

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Antigen:
TMEM174

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM174

Gene Alias:
0610009B10Rik; AA986094; TMEM174; Transmembrane protein 174

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
134288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WUU8

Gene Symbols:
TMEM174

Immunogen:
Recombinant protein corresponding to Human TMEM174

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA558193

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Antigen:
RAPGEF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAPGEF6

Gene Alias:
A530068K01; AI844632; BB085664; C030018K18Rik; KIA001LB; LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 6; mKIAA4052; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; PDZ domain containing guanine nucleotide exchange factor(GEF)1; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ domain-containing guanine nucleotide exchange factor I; PDZGEF2; PDZ-GEF2; RAGEF2; RA-GEF-2; Rap guanine nucleotide exchange factor (GEF) 6; rap guanine nucleotide exchange factor 2; Rap guanine nucleotide exchange factor 6; RAPGEF6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51735

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8TEU7

Gene Symbols:
RAPGEF6

Immunogen:
Recombinant protein corresponding to Human RAPGEF6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA558195

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Antigen:
FLVCR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FLVCR2

Gene Alias:
C14orf58; calcium-chelate transporter; CCT; EPV; feline leukemia virus subgroup C cellular receptor family member 2; feline leukemia virus subgroup C cellular receptor family, member 2; feline leukemia virus subgroup C receptor-related protein 2; FLVCR2; FLVCRL14q; major facilitator superfamily domain containing 7C; MFSD7C; PVHH; transporter

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55640

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UPI3

Gene Symbols:
FLVCR2

Immunogen:
Recombinant protein corresponding to Human FLVCR2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG