PIPA558432

FCHSD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA558432-Each-of-1 In Stock ₹ 47,699.70

PIPA558432 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

FCHSD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FCHSD2

Gene Alias

Carom; F-BAR and double SH3 domains protein 2; FCH and double SH3 domains 2; FCH and double SH3 domains protein 2; FCHSD2; KIAA0769; nervous wreck homolog; NWK; NWK1; Protein nervous wreck 1; SH3 multiple domains 3; SH3 multiple domains protein 3; SH3MD3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9873

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O94868

Gene Symbols

FCHSD2

Immunogen

Recombinant protein corresponding to Human FCHSD2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VEELSASENG DTPWMREIQI SPSPKPHASL PPLPLYDQPP SSPYPSPDKR SSLYFPRSPS ANEKSLHAES PGFSQASRHT PETSYGKLRP VRA Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 89%
  • Adapter protein that plays a role in endocytosis via clathrin-coated pits
  • Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor (PubMed:29887380)
  • Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling (PubMed:30249660)
  • Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits (PubMed:29887380)
  • Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate (PubMed:29887380)
  • When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex
  • Does not promote actin polymerisation in the absence of membranes (PubMed:29887380)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA558432

--


Antigen:
FCHSD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FCHSD2

Gene Alias:
Carom; F-BAR and double SH3 domains protein 2; FCH and double SH3 domains 2; FCH and double SH3 domains protein 2; FCHSD2; KIAA0769; nervous wreck homolog; NWK; NWK1; Protein nervous wreck 1; SH3 multiple domains 3; SH3 multiple domains protein 3; SH3MD3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9873

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O94868

Gene Symbols:
FCHSD2

Immunogen:
Recombinant protein corresponding to Human FCHSD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA558434

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Antigen:
HAL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HAL

Gene Alias:
hal; HIS; histidase; histidine ammonia lyase; histidine ammonia-lyase; histidinemia; Hsd; HSTD; Huth; zgc:136980

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3034

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P42357

Gene Symbols:
HAL

Immunogen:
Recombinant protein corresponding to Human HAL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA558436

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Antigen:
TMTC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMTC3

Gene Alias:
FLJ90492; Protein O-mannosyl-transferase TMTC3; Protein SMILE; SMILE; TMTC3; transmembrane and tetratricopeptide repeat containing 3; transmembrane and TPR repeat-containing protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
160418

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6ZXV5

Gene Symbols:
TMTC3

Immunogen:
Recombinant protein corresponding to Human TMTC3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA558438

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Antigen:
C2CD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C2CD3

Gene Alias:
AU020772; C2 calcium dependent domain containing 3; C2 calcium-dependent domain containing 3; C2 domain-containing protein 3; C2CD3; Hty; OFD14; Protein hearty; RGD1307366

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26005

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q4AC94

Gene Symbols:
C2CD3

Immunogen:
Recombinant protein corresponding to Human C2CD3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG