PIPA559165

SPG11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA559165-Each-of-1 In Stock ₹ 47,015.22

PIPA559165 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SPG11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPG11

Gene Alias

6030465E24Rik; A330015I11; ALS5; C530005A01Rik; CMT2X; Colorectal carcinoma-associated protein; KIAA1840; RGD1562529; spastic paraplegia 11; spastic paraplegia 11 (autosomal recessive); spastic paraplegia 11 protein; Spastic paraplegia 11 protein homolog; spatacsin; Spg11

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80208

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

1.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96JI7

Gene Symbols

SPG11

Immunogen

Recombinant protein corresponding to Human SPG11

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA559176

--

Img

Thermo Scientific

PIPA559703

--

Img

Thermo Scientific

PIPA560314

--

Img

Thermo Scientific

PIPA560464

--

Img

Thermo Scientific

PIPA559404

--

Img

Thermo Scientific

PIPA559472

--

Img

Thermo Scientific

PIPA559691

--

Img

Thermo Scientific

PIPA559096

--

Description

  • Immunogen sequence: IKFPWKLTDA IDEYDVHENV PKVKESNIWK KLSFEEVIAS AILNNKIPEA QTFFRIDSHS AQKLEELIGI GLNLVFDNLK KNNIKEASEL LKNMGFDVKG QLLKICFYTT Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%
  • Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders
  • Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration
  • Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC
  • Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage
  • It is expressed in all structures of the brain, with a high expression in the cerebellum
  • SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC
  • Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene
  • Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA559165

--


Antigen:
SPG11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPG11

Gene Alias:
6030465E24Rik; A330015I11; ALS5; C530005A01Rik; CMT2X; Colorectal carcinoma-associated protein; KIAA1840; RGD1562529; spastic paraplegia 11; spastic paraplegia 11 (autosomal recessive); spastic paraplegia 11 protein; Spastic paraplegia 11 protein homolog; spatacsin; Spg11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80208

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
1.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96JI7

Gene Symbols:
SPG11

Immunogen:
Recombinant protein corresponding to Human SPG11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA559166

--


Antigen:
NEK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEK1

Gene Alias:
D8Ertd790e; DKFZp686D06121; DKFZp686K12169; kat; KIAA1901; kidney, anemia and testis; MGC138800; NEK1; Nek1 serine/threonine- and tyrosine-specific protein kinase; never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related expressed kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA related kinase 1; NIMA-related kinase 1; nimA-related protein kinase 1; NY\ REN55; NY-REN-55; NY-REN-55 antigen; protein-serine/threonine kinase; renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1; SRPS2; SRPS2A; SRTD6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4750

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96PY6

Gene Symbols:
NEK1

Immunogen:
Recombinant protein corresponding to Human NEK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA559168

--


Antigen:
KLC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KLC2

Gene Alias:
8030455F02Rik; AW212649; Kinesin light chain 2; KLC 2; KLC2; KLC-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16594, 309159, 64837

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O88448, Q9H0B6

Gene Symbols:
KLC2

Immunogen:
Recombinant protein corresponding to Human KLC2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA559169

--


Antigen:
N6AMT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eef1akmt1

Gene Alias:
2510005D08Rik; AW045965; Ayu21-96; DMNT2; DNMT2; EEF1A lysine methyltransferase 1; Eef1akmt1; ESP13; eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1; Gt(Ayu21)96Imeg; Gt(pU21)96Imeg; GtAyu21-96; M.HsaIIP; N(6)-adenine-specific DNA methyltransferase 2; N-6 adenine-specific DNA methyltransferase 2 (putative); N6AMT2; Protein-lysine N-methyltransferase N6AMT2; PuMet; RGD1306762; RNMT1; RP11-406H21.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
221143

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WVE0

Gene Symbols:
Eef1akmt1

Immunogen:
Recombinant protein corresponding to Human N6AMT2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG