PIPA559221

SCUBE3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA559221-Each-of-1 In Stock ₹ 47,015.22

PIPA559221 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SCUBE3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCUBE3

Gene Alias

CEGF3; CUB domain and EGF-like repeat containing 3; D030038I21Rik; SCUBE3; signal peptide; signal peptide, CUB and EGF-like domain containing protein 3; signal peptide, CUB and EGF-like domain-containing protein 3; signal peptide, CUB domain and EGF like domain containing 3; signal peptide, CUB domain, EGF-like 3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

222663

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8IX30

Gene Symbols

SCUBE3

Immunogen

Recombinant protein corresponding to Human SCUBE3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VLSIKQRASF KIKDAKCRLH LRNKGKTEEA GRITGPGGAP CSECQVTFIH LKCDSSRKGK GRRARTPPGK EVTRLTLELE AEVRAEETTA S Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%
  • SCUBE3 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and is highly expressed in primary osteoblasts and bones, and to a lesser extent in heart
  • Other studies have shown that overexpression of SCUBE3 in mice induced cardiac hypertrophy, suggesting that it may also play a role in the regulation of cardiac growth
  • SCUBE3 has been shown to be an endogenous TGF-Beta receptor ligand and is thought to promote lung cancer cell mobility and invasiveness
  • In lung cancer cells, the secreted SCUBE3 protein was cleaved by MMP2 and MMP9, allowing the activation of the TGF-Beta receptor, the increase of Smad2/3 transcriptional activity and the upregulation of expression of proteins such as TGF-Beta1, VEGF, Snail, and Slug.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA559221

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Antigen:
SCUBE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCUBE3

Gene Alias:
CEGF3; CUB domain and EGF-like repeat containing 3; D030038I21Rik; SCUBE3; signal peptide; signal peptide, CUB and EGF-like domain containing protein 3; signal peptide, CUB and EGF-like domain-containing protein 3; signal peptide, CUB domain and EGF like domain containing 3; signal peptide, CUB domain, EGF-like 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
222663

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IX30

Gene Symbols:
SCUBE3

Immunogen:
Recombinant protein corresponding to Human SCUBE3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA559222

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Antigen:
Heme oxygenase 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMOX2

Gene Alias:
heme oxygenase (decycling) 2; heme oxygenase 2; heme oxygenase-2 non-reducing isoform; HMOX 2; HMOX2; HO 2; HO2; HO-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3163

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P30519

Gene Symbols:
HMOX2

Immunogen:
Recombinant protein corresponding to Human HMOX2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA559226

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Antigen:
DYNC1I2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DYNC1I2

Gene Alias:
3110079H08Rik; AW554389; Cytoplasmic dynein 1 intermediate chain 2; cytoplasmic dynein intermediate chain 2; cytoplasmic dynein intermediate chain 2 isoform 2.1; cytoplasmic dynein intermediate chain 2 isoform 2.2; cytoplasmic dynein intermediate chain 2 isoform 2.5; DH IC-2; DIC74; DNCI2; DNCIC2; Dync1i2; dynein cytoplasmic 1 intermediate chain 2; dynein intermediate chain 2, cytosolic; dynein, cytoplasmic 1, intermediate chain 2; dynein, cytoplasmic, intermediate chain 2; dynein, cytoplasmic, intermediate polypeptide 2; IC2; oncofetal protein (OFP); testis tissue sperm-binding protein Li 66n

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1781

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q13409

Gene Symbols:
DYNC1I2

Immunogen:
Recombinant protein corresponding to Human DYNC1I2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA559227

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Antigen:
CEP68

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEP68

Gene Alias:
6030463E10Rik; AI481761; BC027174; centrosomal protein 68; centrosomal protein 68kDa; centrosomal protein of 68 kDa; Cep68; Kiaa0582; RGD1309101

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23177

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q76N32

Gene Symbols:
CEP68

Immunogen:
Recombinant protein corresponding to Human CEP68

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG