PIPA559298
DLAT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA559298-Each-of-1 | In Stock | ₹ 51,336.00 |
PIPA559298 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,336.00
GST (18%): ₹ 9,240.48
Total Price: ₹ 60,576.48
Antigen
DLAT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DLAT
Gene Alias
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1737
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P10515
Gene Symbols
DLAT
Immunogen
Recombinant protein corresponding to Human DLAT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LLPALSPTMT MGTVQRWEKK VGEKLSEGDL LAEIETDKAT IGFEVQEEGY LAKILVPEGT RDVPLGTPLC IIVEKEADIS AFADYRPTEV TDLKPQVPPP T Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%
- DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC)
- PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A
- The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A
- Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies
- These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)
- In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed
- PBC eventually leads to cirrhosis and liver failure.
Compare Similar Items
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Antigen: DLAT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DLAT
Gene Alias: 6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1737
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P10515
Gene Symbols: DLAT
Immunogen: Recombinant protein corresponding to Human DLAT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DLAT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DLAT
Gene Alias:
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1737
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P10515
Gene Symbols:
DLAT
Immunogen:
Recombinant protein corresponding to Human DLAT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CDAN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDAN1
Gene Alias: 1500015A01Rik; AI448026; AW492297; CDA1; CDAI; CDA-I; Cdan1; CDAN1A; codanin 1; codanin-1; congenital dyserythropoietic anemia type I; congenital dyserythropoietic anemia, type I; congenital dyserythropoietic anemia, type I (human); discs lost homolog; DLT; PRO1295; UNQ664/PRO1295
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 146059
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8IWY9
Gene Symbols: CDAN1
Immunogen: Recombinant protein corresponding to Human CDAN1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CDAN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDAN1
Gene Alias:
1500015A01Rik; AI448026; AW492297; CDA1; CDAI; CDA-I; Cdan1; CDAN1A; codanin 1; codanin-1; congenital dyserythropoietic anemia type I; congenital dyserythropoietic anemia, type I; congenital dyserythropoietic anemia, type I (human); discs lost homolog; DLT; PRO1295; UNQ664/PRO1295
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
146059
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8IWY9
Gene Symbols:
CDAN1
Immunogen:
Recombinant protein corresponding to Human CDAN1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TRAF3IP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRAF3IP3
Gene Alias: 6030423D04Rik; AI115021; DJ434O14.3; FLJ44151; MGC117354; MGC163289; RGD1304848; T3JAM; TRAF3 interacting Jun N terminal kinase (JNK) activating modulator; TRAF3 interacting protein 3; TRAF3-interacting JNK-activating modulator; TRAF3-interacting JNK-activating modulator-like protein; TRAF3-interacting Jun N-terminal kinase (JNK)-activating modulator; TRAF3-interacting protein 3; Traf3ip3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80342
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9Y228
Gene Symbols: TRAF3IP3
Immunogen: Recombinant protein corresponding to Human TRAF3IP3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TRAF3IP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRAF3IP3
Gene Alias:
6030423D04Rik; AI115021; DJ434O14.3; FLJ44151; MGC117354; MGC163289; RGD1304848; T3JAM; TRAF3 interacting Jun N terminal kinase (JNK) activating modulator; TRAF3 interacting protein 3; TRAF3-interacting JNK-activating modulator; TRAF3-interacting JNK-activating modulator-like protein; TRAF3-interacting Jun N-terminal kinase (JNK)-activating modulator; TRAF3-interacting protein 3; Traf3ip3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80342
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9Y228
Gene Symbols:
TRAF3IP3
Immunogen:
Recombinant protein corresponding to Human TRAF3IP3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: METTL22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: METTL22
Gene Alias: C16orf68; C25H16orf68; LP8272; methyltransferase like 22; methyltransferase-like protein 22; Mettl22; RGD1311433
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79091
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9BUU2
Gene Symbols: METTL22
Immunogen: Recombinant protein corresponding to Human METTL22
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
METTL22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
METTL22
Gene Alias:
C16orf68; C25H16orf68; LP8272; methyltransferase like 22; methyltransferase-like protein 22; Mettl22; RGD1311433
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79091
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9BUU2
Gene Symbols:
METTL22
Immunogen:
Recombinant protein corresponding to Human METTL22
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG