PIPA560177

PAPD5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA560177-Each-of-1 In Stock ₹ 47,528.58

PIPA560177 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

PAPD5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PAPD5

Gene Alias

5730445M16Rik; 5830428A09; GLD4; Non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; PAPD5; poly(A) RNA polymerase D5, non-canonical; Tent4b; Terminal guanylyltransferase; Terminal nucleotidyltransferase 4B; terminal uridylyltransferase 3; Topoisomerase-related function protein 4-2; TRF4-2; TUT3; TUTase 3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64282

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8NDF8

Gene Symbols

PAPD5

Immunogen

Recombinant protein corresponding to Human PAPD5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: QSSSSDVDSD ATPCKTPKQL LCRPSTGNRV GSQDVSLESS QAVGKMQSTQ TTNTSNSTNK SQHGSARLFR SSSKGFQGTT QTSH Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 92%
  • Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation (PubMed:21788334, PubMed:30026317)
  • Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism
  • Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates
  • Doesn't need a cofactor for polyadenylation activity (in vitro) (PubMed:21788334, PubMed:21855801)
  • Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including the glucose transporter SLC2A1/GLUT1 (PubMed:28383716)
  • Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs
  • May play a role in sister chromatid cohesion (PubMed:18172165)
  • Mediates 3' adenylation of the microRNA MIR21 followed by its 3'-to-5' trimming by the exoribonuclease PARN leading to degradation (PubMed:25049417)
  • Mediates 3' adenylation of H/ACA box snoRNAs (small nucleolar RNAs) followed by its 3'-to-5' trimming by the exoribonuclease PARN which enhances snoRNA stability and maturation (PubMed:22442037)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA560177

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Antigen:
PAPD5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAPD5

Gene Alias:
5730445M16Rik; 5830428A09; GLD4; Non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; PAPD5; poly(A) RNA polymerase D5, non-canonical; Tent4b; Terminal guanylyltransferase; Terminal nucleotidyltransferase 4B; terminal uridylyltransferase 3; Topoisomerase-related function protein 4-2; TRF4-2; TUT3; TUTase 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64282

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8NDF8

Gene Symbols:
PAPD5

Immunogen:
Recombinant protein corresponding to Human PAPD5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560181

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Antigen:
ATPBD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPH6

Gene Alias:
5730421E18Rik; ATP binding domain 4; Atpbd4; ATP-binding domain-containing protein 4; diphthamide synthase; Diphthamide synthetase; diphthamine biosynthesis 6; diphthine--ammonia ligase; DPH6; DPH6 homolog; protein DPH6 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q7L8W6

Gene Symbols:
DPH6

Immunogen:
Recombinant protein corresponding to Human ATPBD4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560184

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Antigen:
C15orf40

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C15orf40

Gene Alias:
3110040N11Rik; AI851475; C15orf40; chromosome 15 open reading frame 40; RIKEN cDNA 3110040N11 gene; UPF0235 protein C15orf40; UPF0235 protein C15orf40 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
123207

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WUR7

Gene Symbols:
C15orf40

Immunogen:
Recombinant protein corresponding to Human C15orf40

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560185

--


Antigen:
NALP12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NLRP12

Gene Alias:
CLR19.3; FCAS2; monarch 1; monarch-1; NACHT, leucine rich repeat and PYD containing 12; NACHT, LRR and PYD containing protein 12; NACHT, LRR and PYD domains-containing protein 12; NALP12; NLR family pyrin domain containing 12; NLR family, pyrin domain containing 12; Nlrp12; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12; PAN6; PYPAF7; PYRIN-containing APAF1-like protein 7; regulated by nitric oxide; RNO; RNO2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
91662

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P59046

Gene Symbols:
NLRP12

Immunogen:
Recombinant protein corresponding to Human NALP12

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG