PIPA560217

DACT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA560217-Each-of-1 In Stock ₹ 47,015.22

PIPA560217 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

DACT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DACT3

Gene Alias

Antagonist of beta-catenin Dapper homolog 3; arginine-rich region 1 protein; dact 3; Dact3; Dapper antagonist of catenin 3; dapper homolog 3; dapper homolog 3, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 3; DAPPER3; dishevelled binding antagonist of beta catenin 3; dishevelled-binding antagonist of beta-catenin 3; EG666671; naa-3; RGD1563892; RRR1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

147906

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96B18

Gene Symbols

DACT3

Immunogen

Recombinant protein corresponding to Human DACT3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ALEEQLEALP GLVWDLGQQL GDLSLESGGL EQESGRSSGF YEDPSSTGGP DSPPSTFCGD SGFSGSSSYG RLGPSEP Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%
  • The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases
  • Many members of this pathway are also expressed in the postnatal tissues such as brain
  • One such protein is Dact3, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling
  • Dact3 is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, embryonic CNS, and the adult brain
  • Recent evidence shows that Dact3 acts as a negative regulator Wnt/beta-catenin signaling that is repressed at the transcriptional level in colorectal cancer and this repression is associated with bivalent histone modifications
  • This repression can be reversed by pharmacological agents that targets both histone methylation and deacetylation, suggesting that Dact3 may be a potential target for therapeutic treatment of this cancer
  • At least three isoforms of Dact3 are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA560217

--


Antigen:
DACT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DACT3

Gene Alias:
Antagonist of beta-catenin Dapper homolog 3; arginine-rich region 1 protein; dact 3; Dact3; Dapper antagonist of catenin 3; dapper homolog 3; dapper homolog 3, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 3; DAPPER3; dishevelled binding antagonist of beta catenin 3; dishevelled-binding antagonist of beta-catenin 3; EG666671; naa-3; RGD1563892; RRR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147906

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96B18

Gene Symbols:
DACT3

Immunogen:
Recombinant protein corresponding to Human DACT3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA560219

--


Antigen:
LRRC37A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRRC37A

Gene Alias:
leucine rich repeat containing 37A; leucine-rich repeat-containing protein 37A; LRRC37; LRRC37A; LRRC37A1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9884

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A6NMS7

Gene Symbols:
LRRC37A

Immunogen:
Recombinant protein corresponding to Human LRRC37A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA560220

--


Antigen:
BPIFB6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BPIFB6

Gene Alias:
Bactericidal/permeability-increasing protein-like 3; BPI fold containing family B member 6; BPI fold containing family B, member 6; BPI fold-containing family B member 6; Bpifb6; Bpil3; Gm119; LPLUNC6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
128859

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8NFQ5

Gene Symbols:
BPIFB6

Immunogen:
Recombinant protein corresponding to Human BPIFB6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560221

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Antigen:
GLB1L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLB1L

Gene Alias:
4833408P15Rik; Beta-galactosidase-1-like protein; galactosidase beta 1 like; galactosidase beta 1-like; galactosidase, beta 1-like; Glb1l; testicular tissue protein Li 74; UNQ229/PRO262

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79411

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6UWU2

Gene Symbols:
GLB1L

Immunogen:
Recombinant protein corresponding to Human GLB1L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG