PIPA560260
HLA-DRB5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560260-Each-of-1 | In Stock | ₹ 47,443.02 |
PIPA560260 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,443.02
GST (18%): ₹ 8,539.744
Total Price: ₹ 55,982.764
Antigen
HLA-DRB5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HLA-DRB5
Gene Alias
DR beta-5; DR2-beta-2; DR9; DR-9; DRB1-9 beta chain; dw2; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; hla-dr5; HLA-DRB; HLA-DRB5; human leucocyte antigen DRB5; leukocyte antigen class II; major histocompatibility complex, class II, DR beta 5; MHC class I antigen; MHC class II antigen DRB1*9; MHC class II antigen DRB5; MHC class II HLA beta chain; MHC HLA-DR; MHC HLA-DR-beta cell surface glycoprotein; MHC HLA-DR-beta chain
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3127
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q30154
Gene Symbols
HLA-DRB5
Immunogen
Recombinant protein corresponding to Human HLA-DRB5
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GVGESFTVQR RVEPKVTVYP ARTQT Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 56%
- HLA-DRB5 belongs to the HLA class II beta chain paralogues
- This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane
- It plays a central role in the immune system by presenting peptides derived from extracellular proteins
- Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
- The beta chain is approximately 26-28 kDa and its gene contains 6 exons
- Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
- Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
- Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5
- The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted
- There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Compare Similar Items
Show Difference
Antigen: HLA-DRB5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HLA-DRB5
Gene Alias: DR beta-5; DR2-beta-2; DR9; DR-9; DRB1-9 beta chain; dw2; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; hla-dr5; HLA-DRB; HLA-DRB5; human leucocyte antigen DRB5; leukocyte antigen class II; major histocompatibility complex, class II, DR beta 5; MHC class I antigen; MHC class II antigen DRB1*9; MHC class II antigen DRB5; MHC class II HLA beta chain; MHC HLA-DR; MHC HLA-DR-beta cell surface glycoprotein; MHC HLA-DR-beta chain
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3127
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q30154
Gene Symbols: HLA-DRB5
Immunogen: Recombinant protein corresponding to Human HLA-DRB5
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HLA-DRB5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HLA-DRB5
Gene Alias:
DR beta-5; DR2-beta-2; DR9; DR-9; DRB1-9 beta chain; dw2; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; hla-dr5; HLA-DRB; HLA-DRB5; human leucocyte antigen DRB5; leukocyte antigen class II; major histocompatibility complex, class II, DR beta 5; MHC class I antigen; MHC class II antigen DRB1*9; MHC class II antigen DRB5; MHC class II HLA beta chain; MHC HLA-DR; MHC HLA-DR-beta cell surface glycoprotein; MHC HLA-DR-beta chain
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3127
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q30154
Gene Symbols:
HLA-DRB5
Immunogen:
Recombinant protein corresponding to Human HLA-DRB5
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IRX1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRX1
Gene Alias: Homeodomain protein IRXA1; iroquois homeobox 1; iroquois homeobox protein 1; Iroquois related homeobox 1; Iroquois related homeobox 1 (Drosophila); iroquois-class homeodomain protein IRX-1; Irx1; IRX-5; IRXA1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16371, 79192
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P78414, P81068
Gene Symbols: IRX1
Immunogen: Recombinant protein corresponding to Human IRX1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
IRX1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRX1
Gene Alias:
Homeodomain protein IRXA1; iroquois homeobox 1; iroquois homeobox protein 1; Iroquois related homeobox 1; Iroquois related homeobox 1 (Drosophila); iroquois-class homeodomain protein IRX-1; Irx1; IRX-5; IRXA1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16371, 79192
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P78414, P81068
Gene Symbols:
IRX1
Immunogen:
Recombinant protein corresponding to Human IRX1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM30B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM30B
Gene Alias: 9130011B11Rik; CDC50B; Cell cycle control protein 50B; P4-ATPase flippase complex beta subunit TMEM30B; Tmem30b; Transmembrane protein 30B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 161291
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q3MIR4
Gene Symbols: TMEM30B
Immunogen: Recombinant protein corresponding to Human TMEM30B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM30B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM30B
Gene Alias:
9130011B11Rik; CDC50B; Cell cycle control protein 50B; P4-ATPase flippase complex beta subunit TMEM30B; Tmem30b; Transmembrane protein 30B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
161291
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q3MIR4
Gene Symbols:
TMEM30B
Immunogen:
Recombinant protein corresponding to Human TMEM30B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM196
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM196
Gene Alias: TMEM196; Transmembrane protein 196
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 256130
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5HYL7
Gene Symbols: TMEM196
Immunogen: Recombinant protein corresponding to Human TMEM196
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM196
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM196
Gene Alias:
TMEM196; Transmembrane protein 196
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
256130
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5HYL7
Gene Symbols:
TMEM196
Immunogen:
Recombinant protein corresponding to Human TMEM196
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG