PIPA560313
CABIN1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560313-Each-of-1 | In Stock | ₹ 47,186.34 |
PIPA560313 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,186.34
GST (18%): ₹ 8,493.541
Total Price: ₹ 55,679.881
Antigen
CABIN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CABIN1
Gene Alias
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23523
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9Y6J0
Gene Symbols
CABIN1
Immunogen
Recombinant protein corresponding to Human CABIN1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EPGGKVGLLN HRPVAMDAGD SADQSGERKD KESPRAGPTE PMDTSEATVC HSDLERTPPL LPGRPARDRG PESRPTELSL E Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 68%
- Calcineurin binding protein (Cabin-1) and the corresponding rat homolog, designated Cain, are widely expressed nuclear phosphoproteins that regulate the serine/threonine phosphotase activity of calcineurin and influence T cell signaling and apoptosis
- Calcineurin is required for the transcriptional activation of cytokines and the activation of various transcription factors, including NFAT, NFκB and AP-1, involved in T cell receptor (TCR)-mediated signaling
- The regulation of calcineurin depends on the changes in intracellular calcium concentrations and the activity of protein kinase C
- TCR activation results in PKC inducing the hyperphosphorylation of Cabin-1, which facilitates the high affinity binding of Cabin-1 to calcineurin
- This complex formation, in turn, inhibits calcineurin activity and attenuates TCR-mediated signaling
- Cabin-1 also associates directly with MEF-2 proteins, a family of transcription factors that regulate apoptosis signaling in T cells
- This association between Cabin-1 and MEF-2 leads to the inhibition of MEF-2-mediated gene transcription and the inhibition of apoptosis.
Compare Similar Items
Show Difference
Antigen: CABIN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CABIN1
Gene Alias: A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23523
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9Y6J0
Gene Symbols: CABIN1
Immunogen: Recombinant protein corresponding to Human CABIN1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CABIN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CABIN1
Gene Alias:
A330070M20Rik; CABIN1; CAIN; calcineurin binding protein 1; calcineurin binding protein cabin 1; calcineurin inhibitor; Calcineurin-binding protein cabin-1; KB-318B8.7; KIAA0330; Ppp3in; protein phosphatase 3 inhibitor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23523
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9Y6J0
Gene Symbols:
CABIN1
Immunogen:
Recombinant protein corresponding to Human CABIN1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SPACA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SPACA1
Gene Alias: 1700124L11Rik; 4930540L03Rik; RGD1560284; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; sperm acrosome associated 1; sperm acrosome membrane-associated protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81833
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9HBV2
Gene Symbols: SPACA1
Immunogen: Recombinant protein corresponding to Human SPACA1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SPACA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SPACA1
Gene Alias:
1700124L11Rik; 4930540L03Rik; RGD1560284; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; sperm acrosome associated 1; sperm acrosome membrane-associated protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81833
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9HBV2
Gene Symbols:
SPACA1
Immunogen:
Recombinant protein corresponding to Human SPACA1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: UFSP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ufsp2
Gene Alias: 1810047C23Rik; BHD; C4orf20; RGD1311161; UFM1 specific peptidase 2; UFM1-specific peptidase 2; ufm1-specific protease 2; UfSP2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55325
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NUQ7
Gene Symbols: Ufsp2
Immunogen: Recombinant protein corresponding to Human UFSP2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
UFSP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ufsp2
Gene Alias:
1810047C23Rik; BHD; C4orf20; RGD1311161; UFM1 specific peptidase 2; UFM1-specific peptidase 2; ufm1-specific protease 2; UfSP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55325
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NUQ7
Gene Symbols:
Ufsp2
Immunogen:
Recombinant protein corresponding to Human UFSP2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BPIL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BPIFC
Gene Alias: 4732454E24; bactericidal/permeability-increasing protein-like 2; BPI fold containing family C; BPI fold-containing family C protein; Bpifc; Bpil2; BPI-like 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 254240
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8NFQ6
Gene Symbols: BPIFC
Immunogen: Recombinant protein corresponding to Human BPIL2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BPIL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BPIFC
Gene Alias:
4732454E24; bactericidal/permeability-increasing protein-like 2; BPI fold containing family C; BPI fold-containing family C protein; Bpifc; Bpil2; BPI-like 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
254240
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NFQ6
Gene Symbols:
BPIFC
Immunogen:
Recombinant protein corresponding to Human BPIL2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG