PIPA560317

JMY Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA560317-Each-of-1 In Stock ₹ 47,015.22

PIPA560317 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

JMY

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JMY

Gene Alias

FLJ37870; JMY; junction mediating and regulatory protein, p53 cofactor; junction-mediating and regulatory protein; junction-mediating and -regulatory protein; LOC683593; p300 transcriptional cofactor JMY; similar to junction-mediating and regulatory protein; WAS protein homology region 2 domain containing 1-like 3; WHAMM2; WHDC1L3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

133746

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8N9B5

Gene Symbols

JMY

Immunogen

Recombinant protein corresponding to Human JMY

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VSSVRIVSAS GTVSEEIEVL EMVKEDEAPL ALSDAEQPPP ATELESPAEE CSWAGLFSFQ DLRAVHQQLC SVNSQLEPCL PVFPEEPSGM WTVLF Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 87%
  • JMY acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions
  • In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300
  • Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage
  • In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments
  • Activates the Arp2/3 complex to induce branched actin filament networks
  • Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments
  • Contributes to cell motility by controlling actin dynamics
  • May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments
  • The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA560317

--


Antigen:
JMY

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JMY

Gene Alias:
FLJ37870; JMY; junction mediating and regulatory protein, p53 cofactor; junction-mediating and regulatory protein; junction-mediating and -regulatory protein; LOC683593; p300 transcriptional cofactor JMY; similar to junction-mediating and regulatory protein; WAS protein homology region 2 domain containing 1-like 3; WHAMM2; WHDC1L3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
133746

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8N9B5

Gene Symbols:
JMY

Immunogen:
Recombinant protein corresponding to Human JMY

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560318

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Antigen:
UPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UPK2

Gene Alias:
AW491716; UP2; UPII; UPK2; uroplakin 2; uroplakin II; Uroplakin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7379

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.30 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O00526

Gene Symbols:
UPK2

Immunogen:
Recombinant protein corresponding to Human UPK2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560319

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Antigen:
MTRF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTRF1

Gene Alias:
A830062K05Rik; mitochondrial translational release factor 1; mitochontrial peptide chain release factor 1; MRF1; MRF-1; Mtrf1; MtRF-1; MTTRF1; Peptide chain release factor 1, mitochondrial; RF1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9617

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O75570

Gene Symbols:
MTRF1

Immunogen:
Recombinant protein corresponding to Human MTRF1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA560320

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Antigen:
RHCG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHCG

Gene Alias:
ammonium transporter Rh type C; BB065800; C15orf6; CDRC2; PDRC2; Rh family; Rh family C glycoprotein; rh family type C glycoprotein; Rh family, C glycoprotein; rh glycoprotein kidney; Rh type C glycoprotein; RHCG; Rhesus blood group family type C glycoprotein; Rhesus blood group, C glycoprotein; Rhesus blood group-associated C glycoprotein; Rhesus-associated C glycoprotein; RHGK; SLC42A3; Tumor-related protein DRC2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51458

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UBD6

Gene Symbols:
RHCG

Immunogen:
Recombinant protein corresponding to Human RHCG

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG