PIPA560343
HIC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560343-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA560343 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
HIC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hic1
Gene Alias
AA408311; HIC1; hic-1; hypermethylated in cancer 1; hypermethylated in cancer 1 protein; ZBTB29; Zinc finger and BTB domain-containing protein 29; ZNF901
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3090
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q14526
Gene Symbols
Hic1
Immunogen
Recombinant protein corresponding to Human HIC1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ELLAQTTHFL HDPKVALESL YPLAKFTAEL GLSPDKAAEV LSQGAHLAAG PDGRTIDRFS PT Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%
- Hypermethylated in cancer (HIC-1) was originally identified as a target of p53-induced gene expression
- HIC-1 is deleted in the genetic disorder Miller-Dieker syndrome (MDS), and the expression of HIC-1 is also frequently suppressed in leukemia and various cancers due to the hypermethylation of specific DNA regions and the resulting transcriptional silencing
- These and other studies indicate that HIC-1 acts as a putative tumor suppressor protein that mediates transcriptional repression
- HIC-1 is ubiquitously expressed in adult tissues and its structure is defined by five zinc fingers and an N-terminal broad complex POZ (or BTB) domain
- In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription
- When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated
- Conversely, HIC-1 does not interact with components of the HDAC complex, suggesting that HIC-1-induced transcriptional repression is unassociated with the POZ/BTB domain.
Compare Similar Items
Show Difference
Antigen: HIC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hic1
Gene Alias: AA408311; HIC1; hic-1; hypermethylated in cancer 1; hypermethylated in cancer 1 protein; ZBTB29; Zinc finger and BTB domain-containing protein 29; ZNF901
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3090
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q14526
Gene Symbols: Hic1
Immunogen: Recombinant protein corresponding to Human HIC1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HIC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hic1
Gene Alias:
AA408311; HIC1; hic-1; hypermethylated in cancer 1; hypermethylated in cancer 1 protein; ZBTB29; Zinc finger and BTB domain-containing protein 29; ZNF901
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3090
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q14526
Gene Symbols:
Hic1
Immunogen:
Recombinant protein corresponding to Human HIC1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HMX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMX2
Gene Alias: H6 family homeobox 2; H6 homeo box 2; H6 homeobox 2; H6L; HMX2; homeo box (H6 family) 2; homeobox protein H6 family member 2; Homeobox protein HMX2; homeobox protein Nkx-5.2; MGC32455; NK-related homeobox; Nkx-5.2; Nkx5-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3167
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: A2RU54
Gene Symbols: HMX2
Immunogen: Recombinant protein corresponding to Human HMX2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HMX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMX2
Gene Alias:
H6 family homeobox 2; H6 homeo box 2; H6 homeobox 2; H6L; HMX2; homeo box (H6 family) 2; homeobox protein H6 family member 2; Homeobox protein HMX2; homeobox protein Nkx-5.2; MGC32455; NK-related homeobox; Nkx-5.2; Nkx5-2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3167
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
A2RU54
Gene Symbols:
HMX2
Immunogen:
Recombinant protein corresponding to Human HMX2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C4orf22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C4orf22
Gene Alias: C4orf22; CFAP299; chromosome 4 open reading frame 22; Cilia- and flagella-associated protein 299; uncharacterized protein C4orf22
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 255119
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6V702
Gene Symbols: C4orf22
Immunogen: Recombinant protein corresponding to Human C4orf22
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C4orf22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C4orf22
Gene Alias:
C4orf22; CFAP299; chromosome 4 open reading frame 22; Cilia- and flagella-associated protein 299; uncharacterized protein C4orf22
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
255119
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.8 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6V702
Gene Symbols:
C4orf22
Immunogen:
Recombinant protein corresponding to Human C4orf22
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MARCH3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MARCH3
Gene Alias: 6330411I15Rik; A530081L18Rik; AI843639; E3 ubiquitin-protein ligase MARCH3; MARCH3; MARCH-III; membrane associated ring finger 3; membrane associated ring-CH-type finger 3; membrane-associated ring finger (C3HC4) 3; membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase; membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; RING finger protein 173; RING-type E3 ubiquitin transferase MARCH3; RNF173
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 115123
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86UD3
Gene Symbols: MARCH3
Immunogen: Recombinant protein corresponding to Human MARCH3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MARCH3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MARCH3
Gene Alias:
6330411I15Rik; A530081L18Rik; AI843639; E3 ubiquitin-protein ligase MARCH3; MARCH3; MARCH-III; membrane associated ring finger 3; membrane associated ring-CH-type finger 3; membrane-associated ring finger (C3HC4) 3; membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase; membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; RING finger protein 173; RING-type E3 ubiquitin transferase MARCH3; RNF173
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
115123
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86UD3
Gene Symbols:
MARCH3
Immunogen:
Recombinant protein corresponding to Human MARCH3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG